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TCS PrP Inhibitor 13
CAS No. 34320-83-7
TCS PrP Inhibitor 13( 5-(4-Nitrophenyl)-2-Phenyl-4H-Pyrazol-3-One )
Catalog No. M27727 CAS No. 34320-83-7
TCS PrP Inhibitor 13 is an antiprion agent inhibiting protease-resistant prion protein (PrP-res) accumulation.
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| Size | Price / USD | Stock | Quantity |
| 1 mL x 10 mM in DMSO | 32 | In Stock |
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| 5MG | 30 | In Stock |
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| 10MG | 50 | In Stock |
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| 25MG | 102 | In Stock |
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| 50MG | 155 | In Stock |
|
| 100MG | 239 | In Stock |
|
| 200MG | 340 | In Stock |
|
| 500MG | Get Quote | In Stock |
|
| 1G | Get Quote | In Stock |
|
Biological Information
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Product NameTCS PrP Inhibitor 13
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NoteResearch use only, not for human use.
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Brief DescriptionTCS PrP Inhibitor 13 is an antiprion agent inhibiting protease-resistant prion protein (PrP-res) accumulation.
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DescriptionTCS PrP Inhibitor 13 is an antiprion agent inhibiting protease-resistant prion protein (PrP-res) accumulation.(In Vitro):In Schwannoma cells, administration of 0-500 μM TCS PrP Inhibitor 13 reduces levels of total ERK1/2, pAKT, total FAK, Cyclin D1, PrPC and increases expression of cleaved caspase-3 significantly. TCS PrP Inhibitor 13 also significantly reduces the number of proliferating, Ki67-positive cells and total cell number in Schwannoma cells.
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In VitroTCS PrP Inhibitor 13 (0~500 μM; Schwannoma cells) significantly reduces levels of total ERK1/2, pAKT, total FAK, Cyclin D1, PrPC and significantly increases expression of cleaved caspase-3. TCS PrP Inhibitor 13 (Schwannoma cells) significantly reduces the number of proliferating, Ki67-positive cells and total cell number.
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In Vivo——
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Synonyms5-(4-Nitrophenyl)-2-Phenyl-4H-Pyrazol-3-One
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PathwayOthers
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TargetOther Targets
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Recptor——
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Research Area——
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Indication——
Chemical Information
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CAS Number34320-83-7
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Formula Weight281.271
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Molecular FormulaC15H11N3O3
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Purity>98% (HPLC)
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SolubilityIn Vitro:?DMSO : 100 mg/mL (355.53 mM)
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SMILES[O-][N+](=O)c1ccc(cc1)C1=NN(C(=O)C1)c1ccccc1
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Chemical Name——
Shipping & Storage Information
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Storage(-20℃)
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ShippingWith Ice Pack
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Stability≥ 2 years
Reference
1.Ensslin HK, Kovar KA, Maurer HH. Toxicological detection of the designer drug 3,4-methylenedioxyethylamphetamine (MDE, "Eve") and its metabolites in urine by gas chromatography-mass spectrometry and fluorescence polarization immunoassay. J Chromatogr B Biomed Appl. 1996 Aug 30;683(2):189-97.
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