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SCS
CAS No. 3232-36-8
SCS( Salicylidene salicylhydrazide )
Catalog No. M27708 CAS No. 3232-36-8
SCS a potent selective inhibitor of α2β1γ1θ GABA(A) receptors with a maximum inhibition of 56+/-5% and an IC50 of 32 nM.
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| Size | Price / USD | Stock | Quantity |
| 25MG | 43 | In Stock |
|
| 50MG | 61 | In Stock |
|
| 100MG | 89 | In Stock |
|
| 200MG | Get Quote | In Stock |
|
| 500MG | 216 | In Stock |
|
| 1G | Get Quote | In Stock |
|
Biological Information
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Product NameSCS
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NoteResearch use only, not for human use.
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Brief DescriptionSCS a potent selective inhibitor of α2β1γ1θ GABA(A) receptors with a maximum inhibition of 56+/-5% and an IC50 of 32 nM.
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DescriptionSCS a potent selective inhibitor of α2β1γ1θ GABA(A) receptors with a maximum inhibition of 56+/-5% and an IC50 of 32 nM.
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In Vitro——
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In VivoAnimal Model:BALB/c mice; tonic, phasic and Capsaicin (HY-10448) nociception modelDosage:10, 25, 50, and 75 mg/kg Administration:IP, single dose Result:Produced a significant protection on tonic, phasic and capsaicin nociception in a dose-dependent manner.Animal Model:BALB/c mice, Oxaliplatin (HY-17371)-induced neuropathic nociception model Dosage:50 and 75 mg/kg Administration:IP, single dose Result:Significantly attenuated the paw withdrawal threshold changes associated with Oxaliplatin. Significantly increased the percent antinociception during 30-120 min.
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SynonymsSalicylidene salicylhydrazide
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PathwayOthers
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TargetOther Targets
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RecptorHistamine Receptor|Autophagy|Apoptosis
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Research Area——
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Indication——
Chemical Information
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CAS Number3232-36-8
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Formula Weight256.261
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Molecular FormulaC14H12N2O3
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Purity>98% (HPLC)
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SolubilityIn Vitro:?DMSO : 50 mg/mL (195.11 mM)
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SMILESOc1ccccc1C(=O)NN\C=C1\C=CC=CC1=O
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Chemical Name——
Shipping & Storage Information
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Storage(-20℃)
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ShippingWith Ice Pack
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Stability≥ 2 years
Reference
1.Cui J, et al. Alginic acid induces oxidative stress-mediated hormone secretion disorder, apoptosis and autophagy in mouse granulosa cells and ovaries. Toxicology. 2022;467:153099.
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