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PNU-177864

CAS No. 250266-51-4

PNU-177864( —— )

Catalog No. M27686 CAS No. 250266-51-4

dopamine D3 receptor antagonist.

Purity : >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
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5MG 72 In Stock
10MG 89 In Stock
25MG 202 In Stock
50MG 277 In Stock
100MG 383 In Stock
200MG 533 In Stock
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Biological Information

  • Product Name
    PNU-177864
  • Note
    Research use only, not for human use.
  • Brief Description
    dopamine D3 receptor antagonist.
  • Description
    dopamine D3 receptor antagonist.
  • In Vitro
    ——
  • In Vivo
    Animal Model:Male and female Sprague-Dawley rats (8-9-week-old)Dosage:12.5 mg/kg, 50 mg/kg (for 2 weeks), or 200 mg/kg; 8 mg/kg, 25 mg/kg, or 80 mg/kg (for 4 weeks)Administration:Oral gavage; daily; for 2-4 weeksResult:Induced phospholipidosis in unusual target organs in dogs or rats including epididymis, pituitary, and hair follicles.
  • Synonyms
    ——
  • Pathway
    Others
  • Target
    Other Targets
  • Recptor
    PI3K|Caspase|Bcl-2
  • Research Area
    ——
  • Indication
    ——

Chemical Information

  • CAS Number
    250266-51-4
  • Formula Weight
    438.89
  • Molecular Formula
    C18H21F3N2O3S·HCl
  • Purity
    >98% (HPLC)
  • Solubility
    ——
  • SMILES
    CCCNCCC1=CC=C(NS(C2=CC=C(OC(F)(F)F)C=C2)(=O)=O)C=C1.Cl
  • Chemical Name
    ——

Shipping & Storage Information

  • Storage
    (-20℃)
  • Shipping
    With Ice Pack
  • Stability
    ≥ 2 years

Reference

1.Tomonaga T, et al. Isoflavonoids, genistein, psi-tectorigenin, and orobol, increase cytoplasmic free calcium in isolated rat hepatocytes. Biochem Biophys Res Commun. 1992 Jan 31;182(2):894-9.
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