ML 154
CAS No. 1345964-89-7
ML 154( NCGC84 )
Catalog No. M27660 CAS No. 1345964-89-7
ML 154 is a potent neuropeptide S receptor (NPSR) antagonist.
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| Size | Price / USD | Stock | Quantity |
| 2MG | 69 | In Stock |
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| 5MG | 107 | In Stock |
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| 10MG | 151 | In Stock |
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| 25MG | 278 | In Stock |
|
| 50MG | 390 | In Stock |
|
| 100MG | 539 | In Stock |
|
| 200MG | 728 | In Stock |
|
| 500MG | Get Quote | In Stock |
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| 1G | Get Quote | In Stock |
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Biological Information
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Product NameML 154
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NoteResearch use only, not for human use.
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Brief DescriptionML 154 is a potent neuropeptide S receptor (NPSR) antagonist.
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DescriptionML 154 is a potent neuropeptide S receptor (NPSR) antagonist.
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In VitroWestern Blot Analysis Cell Line:CHO cells expressing NPSR Concentration:0.001 μM, 0.01 μM, 0.1 μM, 1 μM Incubation Time:30 min Result:Exhibited the most potent inhibition on NPS-induced ERK phosphorylation.
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In VivoAnimal Model:Male Wistar rats (300-350 g) injected with alcohol Dosage:1 mg/kg (10% Solutol, 10% N,N-dimethylacetamide, and 80% 10 mM PBS, pH 7.4) Administration:Intraperitoneal injection; once Result:Inhibited alcohol-induced central ERK phosphorylation in vivo.
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SynonymsNCGC84
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PathwayGPCR/G Protein
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TargetNeuropeptide Y Receptor
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RecptorG2019S LRRK2
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Research Area——
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Indication——
Chemical Information
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CAS Number1345964-89-7
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Formula Weight545.48
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Molecular FormulaC29H26BrN2PS
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Purity>98% (HPLC)
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SolubilityIn Vitro:?DMSO : 62.5 mg/mL (114.58 mM)
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SMILES[Br-].Cc1c([n+]2ccccc2n1C\C=C\c1ccccc1)P(=S)(c1ccccc1)c1ccccc1
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Chemical Name——
Shipping & Storage Information
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Storage(-20℃)
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ShippingWith Ice Pack
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Stability≥ 2 years
Reference
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Neuropeptide Y (22-3...
Neuropeptide Y (22-36), a 15 amino acid peptide, is a fragment of Neuropeptide Y.Neuropeptide Y (NPY) is a 36 amino-acid neuropeptide that is involved in various physiological and homeostatic processes in both the central and peripheral nervous systems. NPY has been identified as the most abundant peptide present in the mammalian central nervous system, which consists of the brain and spinal cord. It is secreted alongside other neurotransmitters such as GABA and glutamate.
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Galanin (1-30), huma...
Galanin (1-30), human is a 30-amino acid neuropeptide, and acts as an agonist of GalR1 and GalR2 receptors, with Kis of both 1 nM. Endogenous peptide with multiple endocrine, metabolic and behavioral effects. Has been shown to have an action on intestinal smooth muscle, insulin and somatostatin release, and synaptic neurotransmission.
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Velneperit
Velneperit is potent and selective neuropeptide Y (NPY) Y5 receptor under evaluating for treatment of obesity.
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