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LY 78335

CAS No. 39959-66-5

LY 78335( 1-(2,3-Dichlorophenyl)ethanamine hydrochloride )

Catalog No. M27651 CAS No. 39959-66-5

LY 78335 is a phenylethanolamine-N-methyltransferase (PNMT) inhibitor.

Purity : >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
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Biological Information

  • Product Name
    LY 78335
  • Note
    Research use only, not for human use.
  • Brief Description
    LY 78335 is a phenylethanolamine-N-methyltransferase (PNMT) inhibitor.
  • Description
    LY 78335 is a phenylethanolamine-N-methyltransferase (PNMT) inhibitor.
  • In Vitro
    ——
  • In Vivo
    1-(2,3-Dichlorophenyl)ethanamine hydrochloride (50 mg/kg; i.p. once daily for three days) effects blood pressure of spontaneously hypertensive rats . Animal Model:Adult spontaneously hypertensive rats (SHR) and Wistar Kyoto ratsDosage:50 mg/kg Administration:Intraperitoneal injection; 50 mg/kg; once daily, for 3 consecutive daysResult:Significantly reduced of the blood pressure in spontaneously hypertensive rats, but showed no significant changes in Wistar-Kyoto rats.
  • Synonyms
    1-(2,3-Dichlorophenyl)ethanamine hydrochloride
  • Pathway
    Others
  • Target
    Other Targets
  • Recptor
    Vasopressin receptor 1
  • Research Area
    ——
  • Indication
    ——

Chemical Information

  • CAS Number
    39959-66-5
  • Formula Weight
    226.53
  • Molecular Formula
    C8H10Cl3N
  • Purity
    >98% (HPLC)
  • Solubility
    In Vitro:?H2O : ≥ 100 mg/mL (441.44 mM))
  • SMILES
    Cl.C[C@@H](N)c1cccc(Cl)c1Cl
  • Chemical Name
    ——

Shipping & Storage Information

  • Storage
    (-20℃)
  • Shipping
    With Ice Pack
  • Stability
    ≥ 2 years

Reference

1.Inagawa M, Ichinohe T, Kaneko Y. Felypressin, but not epinephrine, reduces myocardial oxygen tension after an injection of dental local anesthetic solution at routine doses. J Oral Maxillofac Surg. 2010 May;68(5):1013-7.
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