H2L5186303( ZINC33388081 )

Catalog No. M27634 CAS No. 139262-76-3

COA

Datasheet

HNMR

HPLC

MSDS

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Product Name

H2L5186303
Note

Research use only, not for human use.
Brief Description

H2L5186303 is an LPA2 antagonist and can be used in studies about asthma treatment.
Description

H2L5186303 is an LPA2 antagonist and can be used in studies about asthma treatment.(In Vitro):The high cell invasion activity of HT1080-M6 cells is significantly suppressed by H2L5186303.(In Vivo):H2L5186303 shows strong suppressive efficacy when administered before OVA sensitization and challenge, such as suppression of airway hyper responsiveness, inflammatory cytokine levels, mucin production, and eosinophil numbers.
In Vitro

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In Vivo

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Synonyms

ZINC33388081
Pathway

GPCR/G Protein
Target

LPA Receptor
Recptor

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Research Area

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Indication

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CAS Number

139262-76-3
Formula Weight

488.45
Molecular Formula

C26H20N2O8
Purity

>98% (HPLC)
Solubility

In Vitro:?DMSO : 250 mg/mL (511.82 mM)
SMILES

O(C1=CC(OC2=CC=C(NC(/C=C\C(O)=O)=O)C=C2)=CC=C1)C3=CC=C(NC(/C=C\C(O)=O)=O)C=C3
Chemical Name

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1.Gibson Francis S. Synthesis of paclitaxel by protecting the 7-?hydroxyl of baccatin III using a strong base and an electrophile. WO9945001A1.

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