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CYM 50769

CAS No. 1421365-63-0

CYM 50769( —— )

Catalog No. M27619 CAS No. 1421365-63-0

CYM 50769 is a neuropeptide W/B receptor 1 (NPBWR1, GPR7) antagonist(IC50 = 0.12 μM).

Purity : >98% (HPLC)

COA

Datasheet

HNMR

HPLC

MSDS

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25MG	377	In Stock
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100MG	784	In Stock
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Biological Information

Product Name

CYM 50769
Note

Research use only, not for human use.
Brief Description

CYM 50769 is a neuropeptide W/B receptor 1 (NPBWR1, GPR7) antagonist(IC50 = 0.12 μM).
Description

CYM 50769 is a neuropeptide W/B receptor 1 (NPBWR1, GPR7) antagonist(IC50 = 0.12 μM). CYM 50769 inhibited NPW activation of NPBWR1 with a submicromolar IC50, and displayed high selectivity against a broad array of off-targets with pharmaceutical relevance.
In Vitro

CYM 50769 (1 and 3 μM; 30 min) attenuates the NPW-23-induced ATDC5 cell proliferation in a dose-dependent manner. Cell Proliferation Assay Cell Line:ATDC5 (exposed with 200 ng/mL NPW-23 for 24 h)Concentration:1 and 3 μM Incubation Time:30 min Result:Attenuated the NPW-23-induced cell proliferation in a dose-dependent manner.
In Vivo

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Synonyms

——
Pathway

Others
Target

Other Targets
Recptor

——
Research Area

——
Indication

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Chemical Information

CAS Number

1421365-63-0
Formula Weight

416.86
Molecular Formula

C24H17ClN2O3
Purity

>98% (HPLC)
Solubility

In Vitro:?DMSO : 100 mg/mL (239.89 mM)
SMILES

COc1ccc(Oc2c(Cl)cnn(C3c4ccccc4-c4ccccc34)c2=O)cc1
Chemical Name

——

Shipping & Storage Information

Storage

(-20℃)
Shipping

With Ice Pack
Stability

≥ 2 years

Reference

1.Monteiro JP, et al. Toxicity of methoprene as assessed by the use of a model microorganism. Toxicol In Vitro. 2005;19(7):951-956.

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