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BMS 193885
CAS No. 679839-66-8
BMS 193885( BMS193885 )
Catalog No. M27607 CAS No. 679839-66-8
BMS-193885 is an effective and selective neuropeptide Y1 receptor antagonist (IC50: 5.9nM).
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| Size | Price / USD | Stock | Quantity |
| 2MG | 178 | Get Quote |
|
| 5MG | 282 | Get Quote |
|
| 10MG | 358 | Get Quote |
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| 25MG | 718 | Get Quote |
|
| 50MG | 1228 | Get Quote |
|
| 100MG | 1618 | Get Quote |
|
| 200MG | 2428 | Get Quote |
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| 500MG | Get Quote | Get Quote |
|
| 1G | Get Quote | Get Quote |
|
Biological Information
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Product NameBMS 193885
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NoteResearch use only, not for human use.
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Brief DescriptionBMS-193885 is an effective and selective neuropeptide Y1 receptor antagonist (IC50: 5.9nM).
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DescriptionBMS-193885 is an effective and selective neuropeptide Y1 receptor antagonist (IC50: 5.9nM).(In Vitro):BMS 193885 increases the Kd of [(125)I]PeptideYY from 0.35 nM to 0.65 nM without changing the Bmax (0.16 pmol/mg of protein) in SK-N-MC cells that endogenously express the neuropeptide Y(1) receptor. BMS 193885 is a full antagonist with an apparent Kb of 4.5 nM measured by reversal of forskolin-stimulated inhibition of cAMP production by neuropeptide Y.(In Vivo):BMS 193885 (10 mg/kg; i.p.) reduces one-hour neuropeptide Y-induced food intake in satiated rats, as well as spontaneous overnight food consumption. Chronic administration of BMS 193885 (10 mg/kg) i.p. for 44 days significantly reduces food intake and the rate of body weight gain compared to vehicle treated control without developing tolerance or affecting water intake.
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In Vitro——
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In Vivo——
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SynonymsBMS193885
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PathwayOthers
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TargetOther Targets
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Recptor——
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Research Area——
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Indication——
Chemical Information
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CAS Number679839-66-8
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Formula Weight680.799
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Molecular FormulaC36H48N4O9
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Purity>98% (HPLC)
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Solubility——
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SMILES[H][C@@](C)(O)C(O)=O.COC(=O)C1=C(C)NC(C)=C(C1c1cccc(N\C(O)=N\CCCN2CCC(CC2)c2cccc(OC)c2)c1)C(=O)OC
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Chemical Name——
Shipping & Storage Information
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Storage(-20℃)
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ShippingWith Ice Pack
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Stability≥ 2 years
Reference
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Mauritianin
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