8-Hydroxy-DPAT hydrobromide

CAS No. 76135-31-4

8-Hydroxy-DPAT hydrobromide( 8-OH-DPAT hydrobromide )

Catalog No. M27597 CAS No. 76135-31-4

8-Hydroxy-DPAT hydrobromide (8-OH-DPAT hydrobromide) is a potent and selective 5-HT1A agonist with a pIC50 of 8.19. 8-Hydroxy-DPAT hydrobromide has a selectivity of almost 1000 fold for a subtype of the 5-HT1 binding site.

Purity : >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
Size Price / USD Stock Quantity
5MG 35 Get Quote
10MG 58 Get Quote
25MG 125 Get Quote
50MG 230 Get Quote
100MG 410 Get Quote
500MG 888 Get Quote
1G Get Quote Get Quote

Biological Information

  • Product Name
    8-Hydroxy-DPAT hydrobromide
  • Note
    Research use only, not for human use.
  • Brief Description
    8-Hydroxy-DPAT hydrobromide (8-OH-DPAT hydrobromide) is a potent and selective 5-HT1A agonist with a pIC50 of 8.19. 8-Hydroxy-DPAT hydrobromide has a selectivity of almost 1000 fold for a subtype of the 5-HT1 binding site.
  • Description
    8-Hydroxy-DPAT hydrobromide (8-OH-DPAT hydrobromide) is a potent and selective 5-HT1A agonist with a pIC50 of 8.19. 8-Hydroxy-DPAT hydrobromide has a selectivity of almost 1000 fold for a subtype of the 5-HT1 binding site.
  • In Vitro
    ——
  • In Vivo
    ——
  • Synonyms
    8-OH-DPAT hydrobromide
  • Pathway
    Endocrinology/Hormones
  • Target
    5-HT Receptor
  • Recptor
    PARP1
  • Research Area
    ——
  • Indication
    ——

Chemical Information

  • CAS Number
    76135-31-4
  • Formula Weight
    328.29
  • Molecular Formula
    C16H25NO·HBr
  • Purity
    >98% (HPLC)
  • Solubility
    In Vitro:?DMSO : 25 mg/mL (76.15 mM)
  • SMILES
    OC1=C2C[C@H](CCC2=CC=C1)N(CCC)CCC.Br
  • Chemical Name
    ——

Shipping & Storage Information

  • Storage
    (-20℃)
  • Shipping
    With Ice Pack
  • Stability
    ≥ 2 years

Reference

1.Almahli H, Hadchity E, Jaballah MY, Daher R, Ghabbour HA, Kabil MM, Al-Shakliah NS, Eldehna WM. Development of novel synthesized phthalazinone-based PARP-1 inhibitors with apoptosis inducing mechanism in lung cancer. Bioorg Chem. 2018 Apr;77:443-456.
molnova catalog
related products
  • Maprotiline hydrochl...

    Maprotiline is a tetracyclic antidepressant with similar pharmacological properties to tricyclic antidepressants (TCAs).

  • MDL 100009

    MDL 100009, the S-enantiomer of MDL 100151 and the opposite enantiomer of MDL 100907, is a selective antagonist of 5-HT2A.

  • CART (62-76) (rat, h...

    Cocaine- and amphetamine-regulated transcript (CART) peptide fragment that inhibits food intake. Attenuates NPY-induced feeding and decreases food intake in food-restricted goldfish, and induces anxiogenic-like effects in elevated plus-maze test in rats. Modulates the activity of striatal noradrenergic, and corticostrial and hypothalamic serotoninergic systems, with no major effect on dopaminergic pathways in rat brain.