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1-Deoxymannojirimycin hydrochloride

CAS No. 73465-43-7

1-Deoxymannojirimycin hydrochloride( —— )

Catalog No. M27591 CAS No. 73465-43-7

1-Deoxymannojirimycin hydrochloride is a selective α1,2-mannosidase inhibitor(IC50: 20 μM). 1-Deoxymannojirimycin hydrochloride also inhibits HIV‐1 strains and has poor antiviral activity.

Purity : >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
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Biological Information

  • Product Name
    1-Deoxymannojirimycin hydrochloride
  • Note
    Research use only, not for human use.
  • Brief Description
    1-Deoxymannojirimycin hydrochloride is a selective α1,2-mannosidase inhibitor(IC50: 20 μM). 1-Deoxymannojirimycin hydrochloride also inhibits HIV‐1 strains and has poor antiviral activity.
  • Description
    1-Deoxymannojirimycin hydrochloride is a selective α1,2-mannosidase inhibitor(IC50: 20 μM). 1-Deoxymannojirimycin hydrochloride also inhibits HIV‐1 strains and has poor antiviral activity.(In Vitro):Exposure of such mutant virus strains to 1-Deoxymannojirimycin results in an enhanced suppression of mutant virus-induced cytopathicity in CEM cell cultures.When combined with CBAs at concentrations that showed poor if any suppression of mutant virus replication as single drugs, a synergistic antiviral activity of 1-Deoxymannojirimycin was observed.
  • In Vitro
    ——
  • In Vivo
    ——
  • Synonyms
    ——
  • Pathway
    Others
  • Target
    Other Targets
  • Recptor
    PPARβ|PPARδ
  • Research Area
    ——
  • Indication
    ——

Chemical Information

  • CAS Number
    73465-43-7
  • Formula Weight
    199.63
  • Molecular Formula
    C6H14ClNO4
  • Purity
    >98% (HPLC)
  • Solubility
    In Vitro:?H2O : 100 mg/mL (500.93 mM)
  • SMILES
    Cl.OC[C@H]1NC[C@@H](O)[C@@H](O)[C@@H]1O
  • Chemical Name
    ——

Shipping & Storage Information

  • Storage
    (-20℃)
  • Shipping
    With Ice Pack
  • Stability
    ≥ 2 years

Reference

1.Kaupang ?, et al. Synthesis, biological evaluation and molecular modeling studies of the PPARβ/δ antagonist CC618. Eur J Med Chem. 2015 Apr 13;94:229-36.
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