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GW 610
CAS No. 872726-44-8
GW 610( —— )
Catalog No. M27466 CAS No. 872726-44-8
GW 610 is an antitumor benzothiazole that shows growth-inhibitory activity against several cancer cell lines.
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| Size | Price / USD | Stock | Quantity |
| 2MG | 35 | Get Quote |
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| 5MG | 58 | Get Quote |
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| 10MG | 87 | Get Quote |
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| 25MG | 205 | Get Quote |
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| 50MG | 335 | Get Quote |
|
| 100MG | 537 | Get Quote |
|
| 500MG | 1134 | Get Quote |
|
| 1G | Get Quote | Get Quote |
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Biological Information
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Product NameGW 610
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NoteResearch use only, not for human use.
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Brief DescriptionGW 610 is an antitumor benzothiazole that shows growth-inhibitory activity against several cancer cell lines.
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DescriptionGW 610 is an antitumor benzothiazole that shows growth-inhibitory activity against several cancer cell lines. In MCF-7 and MDA 468 human cancer cell lines, potent antiproliferative activity (growth inhibition (GI50) < 0.1 nM) was observed.
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In VitroGW 610 inhibits the proliferation of MCF-7, MDA?468, KM?12, and HCC?2998 cells, with GI50s of <0.1 nM, <0.1 nM, 290 nM, and 0.25 nM, respectively.GW 610 (0.1-1 μM) induces CYP1A1 mRNA and protein in MDA-MB-468, MCF-7, KM12, and HCC2998 cells, whereas CYP2S1 and CYP2W1 are induced only in breast cancer cells.Western Blot Analysis Cell Line:MDA-MB-468, MCF-7, KM12, and HCC2998 cells Concentration:0.1, 1 μM Incubation Time:48 hours Result:Induced CYP1A1 mRNA and protein in all cell lines including KM12 and HCC2998 CRC cells.Induced CYP2S1 and CYP2W1 mRNA and protein expression in MDA-MB-468 and MCF-7 breast cancer cells.
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In Vivo——
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Synonyms——
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PathwayOthers
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TargetOther Targets
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Recptor——
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Research Area——
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Indication——
Chemical Information
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CAS Number872726-44-8
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Formula Weight289.33
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Molecular FormulaC15H12FNO2S
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Purity>98% (HPLC)
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SolubilityIn Vitro:?DMSO : 25 mg/mL (86.41 mM)
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SMILESCOc(ccc(-c1nc(cc(cc2)F)c2s1)c1)c1OC
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Chemical Name——
Shipping & Storage Information
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Storage(-20℃)
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ShippingWith Ice Pack
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Stability≥ 2 years
Reference
1.Pei Feng, et al. Phosphating process for steel pipe. CN110359036B
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