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Ataciguat
CAS No. 254877-67-3
Ataciguat( HMR-1766 )
Catalog No. M27435 CAS No. 254877-67-3
Ataciguat (HMR-1766) is a potent and specific soluble guanylate cyclase (sGC) activator.
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| Size | Price / USD | Stock | Quantity |
| 1 mL x 10 mM in DMSO | 113 | In Stock |
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| 5MG | 77 | In Stock |
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| 10MG | 140 | In Stock |
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| 25MG | 282 | In Stock |
|
| 50MG | 398 | In Stock |
|
| 100MG | 550 | In Stock |
|
| 200MG | Get Quote | In Stock |
|
| 500MG | Get Quote | In Stock |
|
| 1G | Get Quote | In Stock |
|
Biological Information
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Product NameAtaciguat
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NoteResearch use only, not for human use.
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Brief DescriptionAtaciguat (HMR-1766) is a potent and specific soluble guanylate cyclase (sGC) activator.
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DescriptionAtaciguat (HMR-1766) is a potent and specific soluble guanylate cyclase (sGC) activator.(In Vitro):Ataciguat induces the relaxation in aortic rings or coronary rings. In the presence of nitric oxide synthase (NOS) inhibitor, the endothelium effect was abolished to DETA-NO or ataciguat, in both vessels. Ataciguat was able to induce NO production in HUVECs cells. In the presence of NOS inhibitor, the NO production induced by ataciguat was abolished.
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In Vitro——
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In Vivo——
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SynonymsHMR-1766
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PathwayOthers
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TargetOther Targets
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RecptorPGE|ATPase|Potassium Channel
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Research Area——
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Indication——
Chemical Information
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CAS Number254877-67-3
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Formula Weight576.48
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Molecular FormulaC21H19Cl2N3O6S3
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Purity>98% (HPLC)
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SolubilityIn Vitro:?DMSO : 100 mg/mL (173.46 mM)
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SMILESClc1ccc(s1)S(=O)(=O)Nc1ccc(Cl)cc1C(=O)Nc1ccc(cc1)S(=O)(=O)N1CCOCC1
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Chemical Name——
Shipping & Storage Information
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Storage(-20℃)
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ShippingWith Ice Pack
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Stability≥ 2 years
Reference
1.Kim DH, et al. Metabolism of liriodendrin and syringin by human intestinal bacteria and their relation to in vitro cytotoxicity. Arch Pharm Res. 1999 Feb;22(1):30-4.
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