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Narasin (sodium salt)
CAS No. 58331-17-2
Narasin (sodium salt)( HainanMycin | naransin sodium | Naracin sodium salt )
Catalog No. M27432 CAS No. 58331-17-2
Narasin induces tumor necrosis factor-related apoptosis-induced ligand (TRAIL)-mediated apoptosis by ER stress in glioma cells and inhibits NF-κB signaling by suppressing the phosphorylation of IκBα.
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| Size | Price / USD | Stock | Quantity |
| 2MG | 358 | In Stock |
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| 5MG | 491 | In Stock |
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| 25MG | 1890 | In Stock |
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| 100MG | Get Quote | In Stock |
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| 200MG | Get Quote | In Stock |
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| 500MG | Get Quote | In Stock |
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| 1G | Get Quote | In Stock |
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Biological Information
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Product NameNarasin (sodium salt)
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NoteResearch use only, not for human use.
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Brief DescriptionNarasin induces tumor necrosis factor-related apoptosis-induced ligand (TRAIL)-mediated apoptosis by ER stress in glioma cells and inhibits NF-κB signaling by suppressing the phosphorylation of IκBα.
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DescriptionNarasin induces tumor necrosis factor-related apoptosis-induced ligand (TRAIL)-mediated apoptosis by ER stress in glioma cells and inhibits NF-κB signaling by suppressing the phosphorylation of IκBα.(In Vitro):Narasin caused suicidal erythrocyte death or eryptosis. In human erythrocytes, Narasin increased annexin-V-binding indicating cell membrane scrambling with phosphatidylserine translocation to the erythrocyte surface and the decrease of forward scatter reflecting cell shrinkage, which indicated the death of erythrocyte. (In Vivo):Administration of 4-48 p.p.m of narasin in the pelleted feed of New Zealand White rabbits. After 4 weeks, narasin protected rabbits from severe coccidiosis induced by E. flavescens, E. perforans E. Magna, E. Intestinalis, and E. Stiedai. In addition, narasin reduced oocyst output effectively.
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In Vitro——
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In Vivo——
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SynonymsHainanMycin | naransin sodium | Naracin sodium salt
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PathwayApoptosis
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TargetNF-κB
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Recptor——
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Research Area——
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Indication——
Chemical Information
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CAS Number58331-17-2
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Formula Weight787.01
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Molecular FormulaC43H71NaO11
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Purity>98% (HPLC)
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Solubility——
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SMILESCC[C@@H](C([O-])=O)[C@H]1[C@@H](C)C[C@H](C)[C@H]([C@H]([C@H](O)[C@@H](C([C@@H]([C@@H]2[C@@H](C)C[C@@H](C)[C@@]3(C=C[C@@H](O)[C@]4(CC[C@@](C)([C@H]5CC[C@@](CC)(O)C(C)O5)O4)O3)O2)CC)=O)C)C)O1.[Na+]
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Chemical Name——
Shipping & Storage Information
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Storage(-20℃)
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ShippingWith Ice Pack
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Stability≥ 2 years
Reference
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Scandoside
Scandoside, a cyclic enolide that can be isolated from Haemophilus difficile, exhibits anti-inflammatory activity, inhibits the expression levels of inducible nitric oxide synthase (iNOS), cyclooxygenase-2 (COX-2), TNF-α, and IL-6 messenger RNA (mRNA), and inhibits the nuclear transcription factor, kappa-B alpaha (IκB-α), p38, extracellular signal-regulated kinase (ERK) and c-Jun N-terminal kinase (JNK) inhibitor phosphorylation.
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Gue1654
Gue1654 is a selective OXE-R inhibitor that attenuates coronary artery ligation-induced ischemic myocardial injury and cardiomyocyte oxygen/glucose deprivation-induced injury in mice through activation of BCAT1.
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Urolithin B
Urolithin B inhibits NF-κB activity by reducing the phosphorylation and degradation of IκBα, and suppresses the phosphorylation of JNK, ERK, and Akt, and enhances the phosphorylation of AMPK.?Urolithin B is also a regulator of skeletal muscle mass.Urolithin B is one of the gut microbial metabolites of ellagitannins, and has anti-inflammatory and antioxidant effects.
