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Indican
CAS No. 487-60-5
Indican( NSC-87517 | NSC 87517 | NSC87517 | Indoxyl-β-D-glucoside | 3-Indoxyl-beta-D-glucopyranoside )
Catalog No. M27182 CAS No. 487-60-5
Indican is a natural protective compound that is used to protect the liver.
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| Size | Price / USD | Stock | Quantity |
| 1 mL x 10 mM in DMSO | 28 | In Stock |
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| 25MG | 29 | In Stock |
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| 50MG | 37 | In Stock |
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| 100MG | 52 | In Stock |
|
| 200MG | Get Quote | In Stock |
|
| 500MG | Get Quote | In Stock |
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| 1G | Get Quote | In Stock |
|
Biological Information
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Product NameIndican
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NoteResearch use only, not for human use.
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Brief DescriptionIndican is a natural protective compound that is used to protect the liver.
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DescriptionIndican is a natural protective compound that is used to protect the liver.(In Vitro):Oral single doses of Indican at 20, 40 mg/kg increase the systemic exposure of MTX and MRT by inhibiting multiple anion transporters including OAT 1, OAT 3, and MRP 4 via the major metabolite indoxyl sulfate (IS) .
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In Vitro——
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In VivoIndican ((Indoxyl-β-D-glucoside; oral; 20, 40 mg/kg; single dose) increases the systemic exposure and MRT of MTX through inhibition on multiple anion transporters including OAT 1, OAT 3 and MRP 4 by the major metabolite IS. Animal Model:Male Spraguee Dawley rats weighing 330-400 g Dosage:20, 40 mg/kg Administration:Orally Result:Increased the systemic exposure and multidrug resistance-associated protein (MRP) of Methotrexate (MTX; 5.0 mg/kg).
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SynonymsNSC-87517 | NSC 87517 | NSC87517 | Indoxyl-β-D-glucoside | 3-Indoxyl-beta-D-glucopyranoside
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PathwayOthers
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TargetOther Targets
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RecptorCCR2
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Research Area——
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Indication——
Chemical Information
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CAS Number487-60-5
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Formula Weight295.291
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Molecular FormulaC14H17NO6
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Purity>98% (HPLC)
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SolubilityIn Vitro:?DMSO : 100 mg/mL (338.65 mM)
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SMILESOC[C@H]1O[C@@H](Oc2c[nH]c3ccccc23)[C@H](O)[C@@H](O)[C@@H]1O
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Chemical Name——
Shipping & Storage Information
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Storage(-20℃)
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ShippingWith Ice Pack
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Stability≥ 2 years
Reference
1.Moree WJ, et al. Potent antagonists of the CCR2b receptor. Part 3: SAR of the (R)-3-aminopyrrolidine series. Bioorg Med Chem Lett. 2008 Mar 15;18(6):1869-73.
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