N-Bis(2-hydroxypropyl)nitrosamine

Research use only, not for human use.

N-Bis(2-hydroxypropyl)nitrosamine is a carcinogenic agent.

N-Bis(2-hydroxypropyl)nitrosamine is a carcinogenic agent.(In Vivo):The carcinogenic activity of orally administered N-bis(2-hydroxypropyl)-nitrosamine (DHPN) in male Wistar rats was evaluated with respect to its dose. DHPN was administered at two doses, 100 ppm and 500 ppm, in the drinking water to rats for 25 to 52 weeks. Tumors developed in the lung, liver, and thyroid of rats receiving 100 ppm DHPN and in the lung, liver thyroid, esophagus, kidney, and urinary bladder of rats receiving 500 ppm DHPN. The principal target organ was the lung in rats receiving either 100 or 500 ppm DHPN, indicating that the carcinogenic action of these doses of DHPN was similar to that of higher doses previously reported.

N-Bis(2-hydroxypropyl)nitrosamine is an agent with carcinogenic activity.

N-Bis(2-hydroxypropyl)nitrosamine causes the tumors to develop in the lung, liver, and thyroid of rats at a dose of 100 ppm, in the lung, liver thyroid, esophagus, kidney, and urinary bladder of rats at a dose of 500 ppm, and in the lung, liver thyroid, esophagus, kidney, and urinary bladder of rats at both doses. Bisphenol A (BPA) enhances the susceptibility to thyroid carcinoma stimulated by N-Bis(2-hydroxypropyl)nitrosamine (DHPN; 2800 mg/kg) in rats.

DHPN | Di(2-hydroxypropyl)nitrosamine | Diisopropanolnitrosamine

Others

Other Targets

DNA synthesis

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53609-64-6

162.189

C6H14N2O3

>98% (HPLC)

In Vitro:?DMSO : ≥ 125 mg/mL (770.70 mM)

CC(O)CN(CC(C)O)N=O

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(-20℃)

With Ice Pack

≥ 2 years