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5-ALA benzyl ester hydrochloride

CAS No. 163271-32-7

5-ALA benzyl ester hydrochloride( Benzyl-ALA hydrochloride )

Catalog No. M27058 CAS No. 163271-32-7

5-ALA benzyl ester hydrochloride is a protoporphyrin precursor and can be used as a photodetection agent.

Purity : >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
Size Price / USD Stock Quantity
1 mL x 10 mM in DMSO 54 In Stock
5MG 29 In Stock
10MG 48 In Stock
25MG 80 In Stock
50MG 114 In Stock
100MG 169 In Stock
200MG 250 In Stock
500MG 424 In Stock
1G Get Quote In Stock

Biological Information

  • Product Name
    5-ALA benzyl ester hydrochloride
  • Note
    Research use only, not for human use.
  • Brief Description
    5-ALA benzyl ester hydrochloride is a protoporphyrin precursor and can be used as a photodetection agent.
  • Description
    5-ALA benzyl ester hydrochloride is a protoporphyrin precursor and can be used as a photodetection agent.(In Vitro):In colon carcinoma cell lines SW480, 5-ALA benzyl ester hydrochloride (0.6-0.12 mM; 3h) induces PPIX accumulation.(In Vivo):In female CBA/Gy mice, 5-ALA benzyl ester hydrochloride (31 mg/kg; i.v.; 1h) results in a dose-dependent reduction in tumour porphyrin levels.
  • In Vitro
    5-ALA benzyl ester hydrochloride (Benzyl-ALA hydrochloride) (0.6-0.12 mM; 3 h) induces protoporphyrin IX (PPIX) accumulation in colon carcinoma cell lines SW480.
  • In Vivo
    Reducing the dose of 5-ALA benzyl ester hydrochloride (31 mg/kg; i.v. ; 1 hours) results in a dose-dependent reduction in tumour porphyrin levels. Animal Model:Female CBA/Gy mouse (CaNT tumour model)Dosage:31 mg/kg Administration:i.v. ; 1 hours Result:Reducing the dose of 5-ALA benzyl ester hydrochloride resulted in a dose-dependent reduction in the concentration of porphyrins accumulating in the CaNT tumour.
  • Synonyms
    Benzyl-ALA hydrochloride
  • Pathway
    Others
  • Target
    Other Targets
  • Recptor
    Cytochrome C
  • Research Area
    ——
  • Indication
    ——

Chemical Information

  • CAS Number
    163271-32-7
  • Formula Weight
    257.71
  • Molecular Formula
    C12H16ClNO3
  • Purity
    >98% (HPLC)
  • Solubility
    In Vitro:?DMSO : 250 mg/mL (970.08 mM)
  • SMILES
    Cl.NCC(=O)CCC(=O)OCc1ccccc1
  • Chemical Name
    ——

Shipping & Storage Information

  • Storage
    (-20℃)
  • Shipping
    With Ice Pack
  • Stability
    ≥ 2 years

Reference

1.Santucci R, et al. Cytochrome c: An extreme multifunctional protein with a key role in cell fate. Int J Biol Macromol. 2019 Sep 1;136:1237-1246.
molnova catalog
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