NH2-C5-NH-Boc
CAS No. 51644-96-3
NH2-C5-NH-Boc( PROTAC Linker 23 )
Catalog No. M27008 CAS No. 51644-96-3
NH2-C5-NH-Boc (PROTAC Linker 23) is an alkyl chain-based PROTAC linker that can be used in the synthesis of PROTACs.
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
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Biological Information
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Product NameNH2-C5-NH-Boc
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NoteResearch use only, not for human use.
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Brief DescriptionNH2-C5-NH-Boc (PROTAC Linker 23) is an alkyl chain-based PROTAC linker that can be used in the synthesis of PROTACs.
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DescriptionNH2-C5-NH-Boc (PROTAC Linker 23) is an alkyl chain-based PROTAC linker that can be used in the synthesis of PROTACs.
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In VitroPROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins.
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In Vivo——
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SynonymsPROTAC Linker 23
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PathwayOthers
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TargetOther Targets
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RecptorApoptosis
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Research Area——
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Indication——
Chemical Information
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CAS Number51644-96-3
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Formula Weight202.298
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Molecular FormulaC10H22N2O2
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Purity>98% (HPLC)
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SolubilityIn Vitro:?Ethanol : 100 mg/mL (494.34 m)
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SMILESCC(C)(C)OC(=O)NCCCCCN
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Chemical Name——
Shipping & Storage Information
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Storage(-20℃)
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ShippingWith Ice Pack
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Stability≥ 2 years
Reference
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5-Methoxysalicylic a...
5-Methoxysalicylic acid is a natural product used as a useful matrix in the MALDI MS analysis of oligonucleotides when combined with spermine
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Difopein TFA
Difopein (TFA), a specific and competitive inhibitor of 14-3-3 protein (a highly conserved eukaryotic regulatory molecule), blocking the ability of 14-3-3 to bind to target proteins and inhibits 14-3-3/Ligand interactions. Difopein (TFA) leads to induction of apoptosis and enhances the ability of cisplatin to kill cells.
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Cyclo(Phe-Gly)
Cyclo(Phe-Gly) shows weak antagonistic activity against VEGFR2 -CD, it also shows strong inhibitory activity against human cancer cells(KB,KBv200) with LD50 at 6.5 and 11.2 umol/L,respectively.
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