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Bis-Tos-PEG4
CAS No. 37860-51-8
Bis-Tos-PEG4( PROTAC Linker 16 | 1,11-Bis(tosyloxy)-3,6,9-trioxaundecane | Tetraethylene glycol di(p-toluenesulfonate) )
Catalog No. M27007 CAS No. 37860-51-8
Bis-Tos-PEG4 (PROTAC Linker 16) is a PEG-based PROTAC linker can be used in the synthesis of PROTACs.
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| Size | Price / USD | Stock | Quantity |
| 500MG | 37 | In Stock |
|
| 1G | Get Quote | In Stock |
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Biological Information
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Product NameBis-Tos-PEG4
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NoteResearch use only, not for human use.
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Brief DescriptionBis-Tos-PEG4 (PROTAC Linker 16) is a PEG-based PROTAC linker can be used in the synthesis of PROTACs.
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DescriptionBis-Tos-PEG4 (PROTAC Linker 16) is a PEG-based PROTAC linker can be used in the synthesis of PROTACs.(In Vitro):PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins.
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In VitroPROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins.
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In Vivo——
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SynonymsPROTAC Linker 16 | 1,11-Bis(tosyloxy)-3,6,9-trioxaundecane | Tetraethylene glycol di(p-toluenesulfonate)
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PathwayOthers
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TargetOther Targets
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RecptorBcl-2| Caspase-3
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Research Area——
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Indication——
Chemical Information
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CAS Number37860-51-8
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Formula Weight502.59
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Molecular FormulaC22H30O9S2
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Purity>98% (HPLC)
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Solubility——
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SMILESCc1ccc(cc1)S(=O)(=O)OCCOCCOCCOCCOS(=O)(=O)c1ccc(C)cc1
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Chemical Name——
Shipping & Storage Information
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Storage(-20℃)
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ShippingWith Ice Pack
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Stability≥ 2 years
Reference
1.Golla Madhubabu, et al. Allethrin induces oxidative stress, apoptosis and calcium release in rat testicular carcinoma cells (LC540). Toxicol In Vitro. 2014 Dec;28(8):1386-95.
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