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PDEC-NB

CAS No. 874302-76-8

PDEC-NB( 4-Nitrophenyl 2-(Pyridin-2-Yldisulfanyl)Ethyl Carbonate )

Catalog No. M26998 CAS No. 874302-76-8

PDEC-NB is a disulfide cleavable linker used for the antibody-drug conjugate (ADC).

Purity : >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
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Biological Information

  • Product Name
    PDEC-NB
  • Note
    Research use only, not for human use.
  • Brief Description
    PDEC-NB is a disulfide cleavable linker used for the antibody-drug conjugate (ADC).
  • Description
    PDEC-NB is a disulfide cleavable linker used for the antibody-drug conjugate (ADC).
  • In Vitro
    ——
  • In Vivo
    ——
  • Synonyms
    4-Nitrophenyl 2-(Pyridin-2-Yldisulfanyl)Ethyl Carbonate
  • Pathway
    Others
  • Target
    Other Targets
  • Recptor
    α7 nAChR
  • Research Area
    ——
  • Indication
    ——

Chemical Information

  • CAS Number
    874302-76-8
  • Formula Weight
    352.38
  • Molecular Formula
    C14H12N2O5S2
  • Purity
    >98% (HPLC)
  • Solubility
    In Vitro:?DMSO : 100 mg/mL (283.78 mM)
  • SMILES
    [O-][N+](=O)c1ccc(OC(=O)OCCSSc2ccccn2)cc1
  • Chemical Name
    ——

Shipping & Storage Information

  • Storage
    (-20℃)
  • Shipping
    With Ice Pack
  • Stability
    ≥ 2 years

Reference

1.Yue Y, et al. GTS-21 attenuates lipopolysaccharide-induced inflammatory cytokine production in vitro by modulating the Akt and NF-κB signaling pathway through the α7 nicotinic acetylcholine receptor. Int Immunopharmacol. 2015 Dec;29(2):504-512.
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