m-PEG12-OH
CAS No. 2050595-03-2
m-PEG12-OH( Dodecaethylene Glycol Monomethyl Ether )
Catalog No. M26969 CAS No. 2050595-03-2
m-PEG12-OH is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs.
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
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Biological Information
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Product Namem-PEG12-OH
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NoteResearch use only, not for human use.
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Brief Descriptionm-PEG12-OH is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs.
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Descriptionm-PEG12-OH is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs. m-PEG12-OH is also a non-cleavable 12 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs).(In Vitro):PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins. ADCs are comprised of an antibody to which is attached an ADC cytotoxin through an ADC linker.
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In VitroPROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins.
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In Vivo——
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SynonymsDodecaethylene Glycol Monomethyl Ether
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PathwayOthers
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TargetOther Targets
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RecptorDENV NS2B-NS3 protease
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Research Area——
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Indication——
Chemical Information
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CAS Number2050595-03-2
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Formula Weight560.67
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Molecular FormulaC25H52O13
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Purity>98% (HPLC)
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Solubility——
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SMILESCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCO
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Chemical Name——
Shipping & Storage Information
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Storage(-20℃)
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ShippingWith Ice Pack
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Stability≥ 2 years
Reference
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