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Fmoc-NH-PEG10-acid

CAS No. 2101563-45-3

Fmoc-NH-PEG10-acid( —— )

Catalog No. M26961 CAS No. 2101563-45-3

Fmoc-NH-PEG10-acid is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs.

Purity : >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
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Biological Information

  • Product Name
    Fmoc-NH-PEG10-acid
  • Note
    Research use only, not for human use.
  • Brief Description
    Fmoc-NH-PEG10-acid is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs.
  • Description
    Fmoc-NH-PEG10-acid is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs.(In Vitro):PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins.
  • In Vitro
    PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins.
  • In Vivo
    ——
  • Synonyms
    ——
  • Pathway
    Others
  • Target
    Other Targets
  • Recptor
    DHODH
  • Research Area
    ——
  • Indication
    ——

Chemical Information

  • CAS Number
    2101563-45-3
  • Formula Weight
    751.867
  • Molecular Formula
    C38H57NO14
  • Purity
    >98% (HPLC)
  • Solubility
    ——
  • SMILES
    OC(=O)CCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCNC(=O)OCC1c2ccccc2-c2ccccc12
  • Chemical Name
    ——

Shipping & Storage Information

  • Storage
    (-20℃)
  • Shipping
    With Ice Pack
  • Stability
    ≥ 2 years

Reference

1.Shih KC, et al. Development of a human dihydroorotate dehydrogenase (hDHODH) pharma-similarity index approach with scaffold-hopping strategy for the design of novel potential inhibitors. PLoS One. 2014 Feb 4;9(2):e87960.
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