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VH032-cyclopropane-F

CAS No. 2306193-99-5

VH032-cyclopropane-F( VHL ligand 3 | E3 ligase Ligand 19 | Phenolic VH101 )

Catalog No. M26942 CAS No. 2306193-99-5

VH032-cyclopropane-F is a VH032-based VHL ligand. VH032-cyclopropane-F can be connected to the ligand for protein by a linker to form PROTACs. PROTAC 1 is a partial degrader of SMARCA2 and SMARCA4.

Purity : >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
Size Price / USD Stock Quantity
1 mL x 10 mM in DMSO 40 In Stock
5MG 33 In Stock
10MG 50 In Stock
25MG 87 In Stock
50MG 129 In Stock
100MG 198 In Stock
200MG 326 In Stock
500MG Get Quote In Stock
1G Get Quote In Stock
Get Quotation Bulk Inquiry Add to Cart

Biological Information

  • Product Name
    VH032-cyclopropane-F
  • Note
    Research use only, not for human use.
  • Brief Description
    VH032-cyclopropane-F is a VH032-based VHL ligand. VH032-cyclopropane-F can be connected to the ligand for protein by a linker to form PROTACs. PROTAC 1 is a partial degrader of SMARCA2 and SMARCA4.
  • Description
    VH032-cyclopropane-F is a VH032-based VHL ligand. VH032-cyclopropane-F can be connected to the ligand for protein by a linker to form PROTACs. PROTAC 1 is a partial degrader of SMARCA2 and SMARCA4.
  • In Vitro
    ——
  • In Vivo
    ——
  • Synonyms
    VHL ligand 3 | E3 ligase Ligand 19 | Phenolic VH101
  • Pathway
    Others
  • Target
    Other Targets
  • Recptor
    RGS19| RGS4
  • Research Area
    ——
  • Indication
    ——

Chemical Information

  • CAS Number
    2306193-99-5
  • Formula Weight
    532.63
  • Molecular Formula
    C26H33FN4O5S
  • Purity
    >98% (HPLC)
  • Solubility
    In Vitro:?DMSO : 100 mg/mL (187.75 mM)
  • SMILES
    Cc1ncsc1-c1ccc(CNC(=O)[C@@H]2C[C@@H](O)CN2C(=O)[C@@H](NC(=O)C2(F)CC2)C(C)(C)C)c(O)c1
  • Chemical Name
    ——

Shipping & Storage Information

  • Storage
    (-20℃)
  • Shipping
    With Ice Pack
  • Stability
    ≥ 2 years

Reference

1.Blazer LL, et al. Reversible, allosteric small-molecule inhibitors of regulator of G protein signaling proteins. Mol Pharmacol. 2010 Sep;78(3):524-33.
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