Amino-PEG12-amine

CAS No. 361543-12-6

Amino-PEG12-amine( H2N-PEG12-CH2CH2NH2 | PEODA13 )

Catalog No. M26883 CAS No. 361543-12-6

Amino-PEG12-amine is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs.

Purity : >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
Size Price / USD Stock Quantity
5MG 32 In Stock
10MG 39 In Stock
25MG 61 In Stock
50MG 88 In Stock
100MG 143 In Stock
200MG Get Quote In Stock
500MG Get Quote In Stock
1G Get Quote In Stock

Biological Information

  • Product Name
    Amino-PEG12-amine
  • Note
    Research use only, not for human use.
  • Brief Description
    Amino-PEG12-amine is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs.
  • Description
    Amino-PEG12-amine is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs.(In Vitro):PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins.
  • In Vitro
    PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins.
  • In Vivo
    ——
  • Synonyms
    H2N-PEG12-CH2CH2NH2 | PEODA13
  • Pathway
    Others
  • Target
    Other Targets
  • Recptor
    Antimalarial
  • Research Area
    ——
  • Indication
    ——

Chemical Information

  • CAS Number
    361543-12-6
  • Formula Weight
    588.736
  • Molecular Formula
    C26H56N2O12
  • Purity
    >98% (HPLC)
  • Solubility
    ——
  • SMILES
    NCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCN
  • Chemical Name
    ——

Shipping & Storage Information

  • Storage
    (-20℃)
  • Shipping
    With Ice Pack
  • Stability
    ≥ 2 years

Reference

1. Taft BR, et, al. Discovery and Preclinical Pharmacology of INE963, a Potent and Fast-Acting Blood-Stage Antimalarial with a High Barrier to Resistance and Potential for Single-Dose Cures in Uncomplicated Malaria. J Med Chem. 2022 Mar 10;65(5):3798-3813.
molnova catalog
related products
  • Broflanilide

    Broflanilide is metabolized to desmethyl-broflanilide, which is a potent antagonist at the insect resistant-to-dieldrin GABA receptor and inhibits S. litura RDL GABAR with IC50 of 1.3 nM.

  • Guaiacylglycerol-bet...

    Guaiacylglycerol-beta-guaiacyl Ether is degraded by microorganisms and is commonly used as a substrate to mimic microbial degradation of cell walls of lignin-living plants.

  • DL-Menthol

    DL-Menthol has short term toxicity in rats, it plays a role in the induction of surgical anesthesia in fishes, related at least in part to the activation of GABAA receptors.