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α-Cyclodextrin

CAS No. 10016-20-3

α-Cyclodextrin( NSC 269470 | NSC-269470 | NSC269470 | Alfadex )

Catalog No. M26868 CAS No. 10016-20-3

Alfadex is a soluble fiber derived from corn and has beneficial effects on weight management in obese individuals with type 2 diabetes.

Purity : >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
Size Price / USD Stock Quantity
1 mL x 10 mM in DMSO 28 In Stock
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Biological Information

  • Product Name
    α-Cyclodextrin
  • Note
    Research use only, not for human use.
  • Brief Description
    Alfadex is a soluble fiber derived from corn and has beneficial effects on weight management in obese individuals with type 2 diabetes.
  • Description
    Alfadex is a soluble fiber derived from corn and has beneficial effects on weight management in obese individuals with type 2 diabetes.(In Vivo):Alfadex preferentially reduces blood levels of saturated and trans fats in the LDL receptor knockout mice. Two independent in vivo biological test systems were used, a single cell Xenopus oocyte with expressed human aquaporin for cell hydration studies and the nematode Caenorhabditis elegans for testing life span in the treated animals. Alfadex was found to enhance water uptake through aquaporins of oocytes. Furthermore, Alfadex promoted longevity in C. elegans.
  • In Vitro
    ——
  • In Vivo
    ——
  • Synonyms
    NSC 269470 | NSC-269470 | NSC269470 | Alfadex
  • Pathway
    Others
  • Target
    Other Targets
  • Recptor
    SET-PP2A
  • Research Area
    ——
  • Indication
    ——

Chemical Information

  • CAS Number
    10016-20-3
  • Formula Weight
    972.846
  • Molecular Formula
    C36H60O30
  • Purity
    >98% (HPLC)
  • Solubility
    In Vitro:?DMSO : 110 mg/mL (113.07 mM)
  • SMILES
    OC[C@H]1O[C@@H]2O[C@@H]3[C@@H](CO)O[C@H](O[C@@H]4[C@@H](CO)O[C@H](O[C@@H]5[C@@H](CO)O[C@H](O[C@@H]6[C@@H](CO)O[C@H](O[C@@H]7[C@@H](CO)O[C@H](O[C@H]1[C@H](O)[C@H]2O)[C@H](O)[C@H]7O)[C@H](O)[C@H]6O)[C@H](O)[C@H]5O)[C@H](O)[C@H]4O)[C@H](O)[C@H]3O
  • Chemical Name
    ——

Shipping & Storage Information

  • Storage
    (-20℃)
  • Shipping
    With Ice Pack
  • Stability
    ≥ 2 years

Reference

1.Zonta F, et al. Lyn sustains oncogenic signaling in chronic lymphocytic leukemia by strengthening SET-mediated inhibition of PP2A. Blood. 2015;125(24):3747-3755.
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