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Sorafenib-d3
CAS No. 1130115-44-4
Sorafenib-d3( Sorafenib (D3) | Bay 43-9006 (D3) )
Catalog No. M26821 CAS No. 1130115-44-4
Sorafenib-d3 is a deuterium-labeled Sorafenib which is a multikinase inhibitor(IC50s: 6 nM, 20 nM, and 22 nM for Raf-1, B-Raf, and VEGFR-3, respectively).
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| Size | Price / USD | Stock | Quantity |
| 1 mL x 10 mM in DMSO | 202 | In Stock |
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| 5MG | 188 | In Stock |
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| 10MG | 339 | In Stock |
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| 25MG | 561 | In Stock |
|
| 50MG | 796 | In Stock |
|
| 100MG | 1070 | In Stock |
|
| 200MG | Get Quote | In Stock |
|
| 500MG | Get Quote | In Stock |
|
| 1G | Get Quote | In Stock |
|
Biological Information
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Product NameSorafenib-d3
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NoteResearch use only, not for human use.
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Brief DescriptionSorafenib-d3 is a deuterium-labeled Sorafenib which is a multikinase inhibitor(IC50s: 6 nM, 20 nM, and 22 nM for Raf-1, B-Raf, and VEGFR-3, respectively).
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DescriptionSorafenib-d3 is a deuterium-labeled Sorafenib which is a multikinase inhibitor(IC50s: 6 nM, 20 nM, and 22 nM for Raf-1, B-Raf, and VEGFR-3, respectively).
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In Vitro——
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In Vivo——
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SynonymsSorafenib (D3) | Bay 43-9006 (D3)
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PathwayMAPK/ERK Signaling
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TargetRaf
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RecptorTGFβ
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Research Area——
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Indication——
Chemical Information
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CAS Number1130115-44-4
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Formula Weight467.84
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Molecular FormulaC21H16ClF3N4O3
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Purity>98% (HPLC)
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SolubilityIn Vitro:?DMSO : 100 mg/mL (213.75 mM)
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SMILESO(C=1C=C(C(NC([2H])([2H])[2H])=O)N=CC1)C2=CC=C(NC(NC3=CC(C(F)(F)F)=C(Cl)C=C3)=O)C=C2
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Chemical Name——
Shipping & Storage Information
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Storage(-20℃)
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ShippingWith Ice Pack
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Stability≥ 2 years
Reference
1.Bowen C, et al. Mitochondrial-related effects of pentabromophenol, tetrabromobisphenol A, and triphenyl phosphate on murine BV-2 microglia cells. Chemosphere. 2020 Sep;255:126919.
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