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Praliciguat

CAS No. 1628730-49-3

Praliciguat( IW-1973 )

Catalog No. M26793 CAS No. 1628730-49-3

Praliciguat stimulates sGC in HEK-293 cells (EC50: 197 nM). Praliciguat is an effective and orally active soluble guanylate cyclase stimulator.

Purity : >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
Size Price / USD Stock Quantity
1 mL x 10 mM in DMSO 432 In Stock
2MG 218 In Stock
5MG 368 In Stock
10MG 567 In Stock
25MG 905 In Stock
50MG 1200 In Stock
100MG 1609 In Stock
200MG Get Quote In Stock
500MG Get Quote In Stock
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Biological Information

  • Product Name
    Praliciguat
  • Note
    Research use only, not for human use.
  • Brief Description
    Praliciguat stimulates sGC in HEK-293 cells (EC50: 197 nM). Praliciguat is an effective and orally active soluble guanylate cyclase stimulator.
  • Description
    Praliciguat stimulates sGC in HEK-293 cells (EC50: 197 nM). Praliciguat is an effective and orally active soluble guanylate cyclase stimulator. It also enhances NO signaling and acts as a vasodilator.
  • In Vitro
    ——
  • In Vivo
    ——
  • Synonyms
    IW-1973
  • Pathway
    Others
  • Target
    Other Targets
  • Recptor
    Alkyl/ether| Cleavable| PEGs
  • Research Area
    ——
  • Indication
    ——

Chemical Information

  • CAS Number
    1628730-49-3
  • Formula Weight
    534.37
  • Molecular Formula
    C21H14F8N6O2
  • Purity
    >98% (HPLC)
  • Solubility
    In Vitro:?DMSO : 250 mg/mL (467.85 mM)
  • SMILES
    OC(CNc1nc(ncc1F)-c1cc(-c2ccon2)n(Cc2ccccc2F)n1)(C(F)(F)F)C(F)(F)F
  • Chemical Name
    ——

Shipping & Storage Information

  • Storage
    (-20℃)
  • Shipping
    With Ice Pack
  • Stability
    ≥ 2 years

Reference

1.Carston R. Wagner, et al. Protein nanorings. US8236925B1.
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