P110δ-IN-1

CAS No. 1595129-71-7

P110δ-IN-1( ME-401 | P110δ-IN-1 | PWT-143 )

Catalog No. M26780 CAS No. 1595129-71-7

ME-401 is an effective and selective inhibitor of P110δ (IC50: 8.4 nM).

Purity : >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
Size Price / USD Stock Quantity
5MG 80 Get Quote
10MG 140 Get Quote
25MG 267 Get Quote
50MG 507 Get Quote
100MG 714 Get Quote
200MG Get Quote Get Quote
500MG Get Quote Get Quote
1G Get Quote Get Quote

Biological Information

  • Product Name
    P110δ-IN-1
  • Note
    Research use only, not for human use.
  • Brief Description
    ME-401 is an effective and selective inhibitor of P110δ (IC50: 8.4 nM).
  • Description
    ME-401 is an effective and selective inhibitor of P110δ (IC50: 8.4 nM).
  • In Vitro
    ——
  • In Vivo
    ——
  • Synonyms
    ME-401 | P110δ-IN-1 | PWT-143
  • Pathway
    PI3K/Akt/mTOR signaling
  • Target
    PI3K
  • Recptor
    ——
  • Research Area
    ——
  • Indication
    ——

Chemical Information

  • CAS Number
    1595129-71-7
  • Formula Weight
    604.77
  • Molecular Formula
    C31H40N8O3S
  • Purity
    >98% (HPLC)
  • Solubility
    In Vitro:?DMSO : 4.62 mg/mL (7.64 mM)
  • SMILES
    CN1CCC(CC1)c1ccccc1CC(C)(C)Nc1nc(nc(n1)-n1c(nc2ccccc12)S(C)(=O)=O)N1CCOCC1
  • Chemical Name
    ——

Shipping & Storage Information

  • Storage
    (-20℃)
  • Shipping
    With Ice Pack
  • Stability
    ≥ 2 years

Reference

1.Gardiner J, et al. The phospholipase A2 inhibitor, aristolochic acid, disrupts cortical microtubule arrays and root growth in Arabidopsis. Plant Biol (Stuttg). 2008 Nov;10(6):725-31.
molnova catalog
related products
  • CL27c

    CL27c is a cell-permeable, inhaled lipophilic ester prodrug of CL27e, which is a potent, selective pan-class I PI3K inhibitor, CL27c is inactive in PI3K enzymatic assay.

  • AS-041164

    AS-041164 is a selective and orally active PI3Kγ isoform inhibitor(IC50 of 70 nM), and shows less activity against PI3Kα, PI3Kβ, and PI3Kδ (IC50s of 240 nM, 1.45 μM, and 1.70 μM, respectively).

  • Zandelisib

    Zandelisib is an inhibitor of phosphatidylinositol 3-kinase (PI3K)(p110δ, IC50 of 3.5 nM), and with antineoplastic activity.