N,N'-Diacetyl-L-cystine( DiNAC )

Catalog No. M26768 CAS No. 5545-17-5

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Product Name

N,N'-Diacetyl-L-cystine
Note

Research use only, not for human use.
Brief Description

N,N'-Diacetyl-L-cystine is the disulphide dimer of N-acetylcysteine with immunomodulating properties.
Description

N,N'-Diacetyl-L-cystine is the disulphide dimer of N-acetylcysteine with immunomodulating properties. N,N'-diacetyl-L-cystine also has antiatherosclerotic effects in Watanabe-heritable hyperlipidemic rabbit (WHHL) rabbits. N,N'-diacetyl-L-cystine is also an effective and orally active modulator of contact sensitivity/delayed-type hypersensitivity reactions in rodents.(In Vivo):N,N'-Diacetyl-L-cystine (DiNAC; 0-973.11 μg/kg; p.o.; daily; for 12 weeks; WHHL rabbits) treatment decreases by 50% thoracic aorta atherosclerosis. However, it has no affecting plasma lipid levels.
In Vitro

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In Vivo

N,N'-Diacetyl-L-cystine (DiNAC; 0-973.11 μg/kg; oral administration; daily; for 12 weeks; WHHL rabbits) treatment reduces by 50% thoracic aorta atherosclerosis, without affecting plasma lipid levels. Animal Model:Male heritable hyperlipidemic rabbit (WHHL) rabbits (10-22 weeks) Dosage:0 μg/kg, 9.73 μg/kg, or 973.11 μg/kg Administration:Oral administration; daily; for 12 weeks Result:Reduced by 50% thoracic aorta atherosclerosis, without affecting plasma lipid levels.
Synonyms

DiNAC
Pathway

Others
Target

Other Targets
Recptor

CDK4/CyclinD1| CDK6/CyclinD3
Research Area

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Indication

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1.1. Ping Chen, et al. 2-amino-pyridine or 2-amino-pyrimidine derivatives as cyclin dependent kinase inhibitors. WO2019207463A1.

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