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Indobufen
CAS No. 63610-08-2
Indobufen( Ibustrin )
Catalog No. M26717 CAS No. 63610-08-2
Indobufen is an inhibitor of platelet aggregation and is a reversible platelet cyclooxygenase (Cox) activity inhibitor. Indobufen suppresses thromboxane A2 (TxA2) synthesis. Indobufen down-regulates tissue factor (TF) in monocytes.
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| Size | Price / USD | Stock | Quantity |
| 10MG | 29 | In Stock |
|
| 25MG | 45 | In Stock |
|
| 50MG | 63 | In Stock |
|
| 100MG | 88 | In Stock |
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| 200MG | Get Quote | In Stock |
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| 500MG | 219 | In Stock |
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| 1G | Get Quote | In Stock |
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Biological Information
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Product NameIndobufen
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NoteResearch use only, not for human use.
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Brief DescriptionIndobufen is an inhibitor of platelet aggregation and is a reversible platelet cyclooxygenase (Cox) activity inhibitor. Indobufen suppresses thromboxane A2 (TxA2) synthesis. Indobufen down-regulates tissue factor (TF) in monocytes.
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DescriptionIndobufen is an inhibitor of platelet aggregation and is a reversible platelet cyclooxygenase (Cox) activity inhibitor. Indobufen suppresses thromboxane A2 (TxA2) synthesis. Indobufen down-regulates tissue factor (TF) in monocytes.(In Vitro):Indobufen suppresses TxA2 but not PGE2 synthesis in LPS-stimulated monocytes. Indobufen causes the extent of ERK1/2 phosphorylation, whereas the levels of phosphorylated p38 are unaltered. Indobufen does not affect both Cox-1 and Cox-2 protein, whereas Indobufen reduces TxB2 levels.
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In VitroIndobufen does not affect both Cox-1 and Cox-2 protein, whereas Indobufen reduces TxB2 levels. Indobufen inhibits TxA2 but not PGE2 synthesis in LPS-stimulated monocytes. Indobufen reduces the extent of ERK1/2 phosphorylation, whereas the levels of phosphorylated p38 are unaltered.
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In Vivo——
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SynonymsIbustrin
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PathwayChromatin/Epigenetic
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TargetCOX
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RecptorRSV
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Research Area——
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Indication——
Chemical Information
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CAS Number63610-08-2
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Formula Weight295.338
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Molecular FormulaC18H17NO3
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Purity>98% (HPLC)
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SolubilityIn Vitro:?DMSO : 250 mg/mL (846.51 mM)
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SMILESCCC(C(O)=O)c1ccc(cc1)N1Cc2ccccc2C1=O
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Chemical Name——
Shipping & Storage Information
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Storage(-20℃)
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ShippingWith Ice Pack
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Stability≥ 2 years
Reference
1.Lundin A, et al. Two novel fusion inhibitors of human respiratory syncytial virus. Antiviral Res. 2010 Dec;88(3):317-24.
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