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Imirestat

CAS No. 89391-50-4

Imirestat( AL 1576 | Alcon 1576 | HOE 843 )

Catalog No. M26715 CAS No. 89391-50-4

Imirestat is an aldose reductase inhibitor that can be used in diabetes research.

Purity : >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
Size Price / USD Stock Quantity
5MG 295 Get Quote
10MG 507 Get Quote
25MG 801 Get Quote
50MG 1107 Get Quote
100MG 1503 Get Quote
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Biological Information

  • Product Name
    Imirestat
  • Note
    Research use only, not for human use.
  • Brief Description
    Imirestat is an aldose reductase inhibitor that can be used in diabetes research.
  • Description
    Imirestat is an aldose reductase inhibitor that can be used in diabetes research.(In Vivo):Administration of 1 mg/kg Imirestat increased nerve conduction velocity, however, had no effect on resistance to hypoxic conduction block or deficits in insulin-stimulated Uban-sensitive ATPase activity.
  • In Vitro
    ——
  • In Vivo
    Imirestat (1 mg/kg) improves nerve conduction velocity but is without effect upon the resistance to hypoxic conduction blockade or the deficit in insulin-stimulated oubain-sensitive ATPase activity.
  • Synonyms
    AL 1576 | Alcon 1576 | HOE 843
  • Pathway
    Endocrinology/Hormones
  • Target
    Reductase
  • Recptor
    SIRT1
  • Research Area
    ——
  • Indication
    ——

Chemical Information

  • CAS Number
    89391-50-4
  • Formula Weight
    286.238
  • Molecular Formula
    C15H8F2N2O2
  • Purity
    >98% (HPLC)
  • Solubility
    In Vitro:?DMSO : 83.33 mg/mL (291.13 mM)
  • SMILES
    Fc1ccc2-c3ccc(F)cc3C3(NC(=O)NC3=O)c2c1
  • Chemical Name
    ——

Shipping & Storage Information

  • Storage
    (-20℃)
  • Shipping
    With Ice Pack
  • Stability
    ≥ 2 years

Reference

1.Napper AD, et al. Discovery of indoles as potent and selective inhibitors of the deacetylase SIRT1. J Med Chem. 2005 Dec 15;48(25):8045-54.
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