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Fluorofenidone
CAS No. 848353-85-5
Fluorofenidone( AKF-PD )
Catalog No. M26688 CAS No. 848353-85-5
Fluorofenidone attenuates the progression of renal interstitial fibrosis partly by suppressing NADPH oxidase and extracellular matrix (ECM) deposition via the PI3K/Akt signalling pathway.
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| Size | Price / USD | Stock | Quantity |
| 1 mL x 10 mM in DMSO | 49 | In Stock |
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| 2MG | 29 | In Stock |
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| 5MG | 45 | In Stock |
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| 10MG | 73 | In Stock |
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| 25MG | 150 | In Stock |
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| 50MG | 267 | In Stock |
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| 100MG | 384 | In Stock |
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| 200MG | 541 | In Stock |
|
| 500MG | Get Quote | In Stock |
|
| 1G | Get Quote | In Stock |
|
Biological Information
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Product NameFluorofenidone
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NoteResearch use only, not for human use.
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Brief DescriptionFluorofenidone attenuates the progression of renal interstitial fibrosis partly by suppressing NADPH oxidase and extracellular matrix (ECM) deposition via the PI3K/Akt signalling pathway.
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DescriptionFluorofenidone attenuates the progression of renal interstitial fibrosis partly by suppressing NADPH oxidase and extracellular matrix (ECM) deposition via the PI3K/Akt signalling pathway. Fluorofenidone is an analogue of AMR69. Which displays equivalent lower toxicity, antifibrotic activity, and longer half-life.
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In Vitro——
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In Vivo——
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SynonymsAKF-PD
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PathwayOthers
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TargetOther Targets
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Recptor——
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Research Area——
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Indication——
Chemical Information
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CAS Number848353-85-5
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Formula Weight203.216
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Molecular FormulaC12H10FNO
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Purity>98% (HPLC)
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SolubilityIn Vitro:?DMSO : 140 mg/mL (688.94 mM)
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SMILESCc1ccc(=O)n(c1)-c1cccc(F)c1
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Chemical Name——
Shipping & Storage Information
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Storage(-20℃)
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ShippingWith Ice Pack
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Stability≥ 2 years
Reference
1.Shi J, et al. Sacubitril Is Selectively Activated by Carboxylesterase 1 (CES1) in the Liver and the Activation Is Affected by CES1 Genetic Variation. Drug Metab Dispos. 2016 Apr;44(4):554-9.
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