Cart
sales@molnova.com
Caracemide
CAS No. 81424-67-1
Caracemide( NSC-253272 )
Catalog No. M26639 CAS No. 81424-67-1
Caracemide inhibits the enzyme ribonucleotide reductase of Escherichia coli. Caracemide can be used in anticancer studies.
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| Size | Price / USD | Stock | Quantity |
| 1 mL x 10 mM in DMSO | 39 | In Stock |
|
| 5MG | 36 | In Stock |
|
| 10MG | 50 | In Stock |
|
| 25MG | 90 | In Stock |
|
| 100MG | Get Quote | In Stock |
|
| 200MG | Get Quote | In Stock |
|
| 500MG | Get Quote | In Stock |
|
| 1G | Get Quote | In Stock |
|
Biological Information
-
Product NameCaracemide
-
NoteResearch use only, not for human use.
-
Brief DescriptionCaracemide inhibits the enzyme ribonucleotide reductase of Escherichia coli. Caracemide can be used in anticancer studies.
-
DescriptionCaracemide inhibits the enzyme ribonucleotide reductase of Escherichia coli. Caracemide can be used in anticancer studies.(In Vitro):Caracemide produces severe central nervous system (CNS) toxicity because of the toxic metabolite, methylisocyanate (MIC). Caracemide inactivates R1 by covalent modification at the substrate-binding site.(In Vivo):After administration of Caracemide (6.6 mg/kg;i.p.), the mercapturic acid derivative AMCC was identified in rats urine.
-
In VitroCaracemide inactivates R1 by covalent modification at the substrate-binding site and has a toxic metabolite, methylisocyanate (MIC), in vivo.
-
In VivoThe mercapturic acid derivative AMCC was identified in urine rats following administration to rats of a single i.p. dose (6.6 mg/kg) of caracemide (NSC-253272). .
-
SynonymsNSC-253272
-
PathwayOthers
-
TargetOther Targets
-
RecptorAnti-infection| Bacterial
-
Research Area——
-
Indication——
Chemical Information
-
CAS Number81424-67-1
-
Formula Weight189.171
-
Molecular FormulaC6H11N3O4
-
Purity>98% (HPLC)
-
SolubilityIn Vitro:?DMSO : 100 mg/mL (528.63 mM)
-
SMILESCNC(=O)ON(C(C)=O)C(=O)NC
-
Chemical Name——
Shipping & Storage Information
-
Storage(-20℃)
-
ShippingWith Ice Pack
-
Stability≥ 2 years
Reference
1.Basanti LalHiran, et al. Oxidation of 3,4,5-trimethoxybenzaldehyde by pyridinium fluorochromate in N,N-dimethyl formamide medium: A kinetic and mechanistic study. Arabian Journal of Chemistry. Volume 9, Supplement 1, September 2016, Pages S440-S445
molnova catalog
related products
-
Gatipotuzumab
Gatipotuzumab (PankoMab) is a novel humanized monoclonal antibody conjugated to the tumor-associated epitope of mucin 1 (TA-MUC1) with potential anti-tumor activity for the study of recurrent epithelial ovarian cancer.
-
FGIN-1-27
FGIN-1-27 is a high-affinity agonist of the translocator protein and a specific peripheral benzodiazepine receptor (PBR) ligand(Ki = 5.0 nM).
-
Zinquin ethyl ester
Zinquin ethyl ester is a cell membrane-penetrating and selective fluorescent probe for zinc ions that measures intracellular levels of Zn(2+) and Ca(2+) ions and can be used to stain early embryos.
