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Bevenopran
CAS No. 676500-67-7
Bevenopran( CB-5945 | ADL-5945 )
Catalog No. M26628 CAS No. 676500-67-7
Bevenopran is a peripheral antagonist of μ-opioid receptor and can be used in studies about the treatment of opioid-induced bowel dysfunction.
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| Size | Price / USD | Stock | Quantity |
| 1 mL x 10 mM in DMSO | 145 | In Stock |
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| 5MG | 132 | In Stock |
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| 10MG | 198 | In Stock |
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| 25MG | 316 | In Stock |
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| 50MG | 421 | In Stock |
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| 100MG | 551 | In Stock |
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| 200MG | 728 | In Stock |
|
| 500MG | Get Quote | In Stock |
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| 1G | Get Quote | In Stock |
|
Biological Information
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Product NameBevenopran
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NoteResearch use only, not for human use.
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Brief DescriptionBevenopran is a peripheral antagonist of μ-opioid receptor and can be used in studies about the treatment of opioid-induced bowel dysfunction.
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DescriptionBevenopran is a peripheral antagonist of μ-opioid receptor and can be used in studies about the treatment of opioid-induced bowel dysfunction.(In Vivo):Bevenopran tends to increase bowel movement (BM) frequency, especially for 0.1 mg twice daily and 4 mg daily, respectively.
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In Vitro——
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In VivoBevenopran is a peripheral μ-opioid receptor antagonist. Bevenopran is currently under investigation for the treatment of opioid-induced bowel dysfunction (OBD). Bevenopran tends to increase bowel movement (BM) frequency, especially for 0.1 mg twice daily and 4 mg daily, respectively.
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SynonymsCB-5945 | ADL-5945
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PathwayEndocrinology/Hormones
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TargetOpioid Receptor
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RecptorAcidic mammalian chitinase (AMCase)| Chitotriosidase (CHIT1)
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Research Area——
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Indication——
Chemical Information
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CAS Number676500-67-7
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Formula Weight386.452
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Molecular FormulaC20H26N4O4
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Purity>98% (HPLC)
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SolubilityIn Vitro:?DMSO : 125 mg/mL (323.47 mM)
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SMILESCOc1cc(CNCCC2CCOCC2)ccc1Oc1cnc(cn1)C(N)=O
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Chemical Name——
Shipping & Storage Information
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Storage(-20℃)
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ShippingWith Ice Pack
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Stability≥ 2 years
Reference
1.Robert Koralewski, et al. Discovery of OATD-01, a First-in-Class Chitinase Inhibitor as Potential New Therapeutics for Idiopathic Pulmonary Fibrosis. J Med Chem. 2020 Dec 24;63(24):15527-15540.
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