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AZ-Dyrk1B-33
CAS No. 1679330-37-0
AZ-Dyrk1B-33( 3-(2-Methyl-4-pyrimidinyl)-1-(phenylmethyl)-1H-pyrrolo[2,3-c]pyridine )
Catalog No. M26618 CAS No. 1679330-37-0
AZ-Dyrk1B-33 is a potent and selective Dyrk1B kinase inhibitor with an IC50 of 7 nM.
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| Size | Price / USD | Stock | Quantity |
| 1 mL x 10 mM in DMSO | 102 | In Stock |
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| 5MG | 93 | In Stock |
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| 10MG | 150 | In Stock |
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| 25MG | 304 | In Stock |
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| 50MG | 432 | In Stock |
|
| 100MG | 603 | In Stock |
|
| 200MG | 814 | In Stock |
|
| 500MG | Get Quote | In Stock |
|
| 1G | Get Quote | In Stock |
|
Biological Information
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Product NameAZ-Dyrk1B-33
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NoteResearch use only, not for human use.
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Brief DescriptionAZ-Dyrk1B-33 is a potent and selective Dyrk1B kinase inhibitor with an IC50 of 7 nM.
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DescriptionAZ-Dyrk1B-33 is a potent and selective Dyrk1B kinase inhibitor with an IC50 of 7 nM.(In Vitro):Administration of AZ-Dyrk1B-33 shows inhibition of phosphorylation of Dyrk pS421 in cells with an IC50 of 0.192 μM and no effect in sensitization.
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In VitroAZ-Dyrk1B-33 shows inhibition of phosphorylation of Dyrk pS421 in cells with an IC50 of 0.192 μM.AZ-Dyrk1B-33 shows no effect in sensitization.
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In Vivo——
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Synonyms3-(2-Methyl-4-pyrimidinyl)-1-(phenylmethyl)-1H-pyrrolo[2,3-c]pyridine
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PathwayOthers
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TargetOther Targets
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RecptorCYP73A
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Research Area——
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Indication——
Chemical Information
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CAS Number1679330-37-0
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Formula Weight300.365
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Molecular FormulaC19H16N4
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Purity>98% (HPLC)
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SolubilityIn Vitro:?DMSO : 125 mg/mL (416.17 mM)
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SMILESCc1nccc(n1)-c1cn(Cc2ccccc2)c2cnccc12
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Chemical Name——
Shipping & Storage Information
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Storage(-20℃)
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ShippingWith Ice Pack
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Stability≥ 2 years
Reference
1.1. Schalk M, et al, Werck-Reichhart D. Piperonylic acid, a selective, mechanism-based inactivator of the trans-cinnamate 4-hydroxylase: A new tool to control the flux of metabolites in the phenylpropanoid pathway. Plant Physiol. 1998;118(1):209‐218.
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