AZ-Dyrk1B-33

CAS No. 1679330-37-0

AZ-Dyrk1B-33( 3-(2-Methyl-4-pyrimidinyl)-1-(phenylmethyl)-1H-pyrrolo[2,3-c]pyridine )

Catalog No. M26618 CAS No. 1679330-37-0

AZ-Dyrk1B-33 is a potent and selective Dyrk1B kinase inhibitor with an IC50 of 7 nM.

Purity : >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
Size Price / USD Stock Quantity
1 mL x 10 mM in DMSO 102 In Stock
5MG 93 In Stock
10MG 150 In Stock
25MG 304 In Stock
50MG 432 In Stock
100MG 603 In Stock
200MG 814 In Stock
500MG Get Quote In Stock
1G Get Quote In Stock

Biological Information

  • Product Name
    AZ-Dyrk1B-33
  • Note
    Research use only, not for human use.
  • Brief Description
    AZ-Dyrk1B-33 is a potent and selective Dyrk1B kinase inhibitor with an IC50 of 7 nM.
  • Description
    AZ-Dyrk1B-33 is a potent and selective Dyrk1B kinase inhibitor with an IC50 of 7 nM.(In Vitro):Administration of AZ-Dyrk1B-33 shows inhibition of phosphorylation of Dyrk pS421 in cells with an IC50 of 0.192 μM and no effect in sensitization.
  • In Vitro
    AZ-Dyrk1B-33 shows inhibition of phosphorylation of Dyrk pS421 in cells with an IC50 of 0.192 μM.AZ-Dyrk1B-33 shows no effect in sensitization.
  • In Vivo
    ——
  • Synonyms
    3-(2-Methyl-4-pyrimidinyl)-1-(phenylmethyl)-1H-pyrrolo[2,3-c]pyridine
  • Pathway
    Others
  • Target
    Other Targets
  • Recptor
    CYP73A
  • Research Area
    ——
  • Indication
    ——

Chemical Information

  • CAS Number
    1679330-37-0
  • Formula Weight
    300.365
  • Molecular Formula
    C19H16N4
  • Purity
    >98% (HPLC)
  • Solubility
    In Vitro:?DMSO : 125 mg/mL (416.17 mM)
  • SMILES
    Cc1nccc(n1)-c1cn(Cc2ccccc2)c2cnccc12
  • Chemical Name
    ——

Shipping & Storage Information

  • Storage
    (-20℃)
  • Shipping
    With Ice Pack
  • Stability
    ≥ 2 years

Reference

1.1. Schalk M, et al, Werck-Reichhart D. Piperonylic acid, a selective, mechanism-based inactivator of the trans-cinnamate 4-hydroxylase: A new tool to control the flux of metabolites in the phenylpropanoid pathway. Plant Physiol. 1998;118(1):209‐218.
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