Cart
sales@molnova.com
ADAMTS-5 Inhibitor
CAS No. 929634-33-3
ADAMTS-5 Inhibitor( —— )
Catalog No. M26598 CAS No. 929634-33-3
ADAMTS-5 Inhibitor is a potent ADAMTS-5 (aggrecanase-2) inhibitor, with an IC50 of 1.1 μM. ADAMTS-5 Inhibitor shows >40-fold functional selectivity over ADAMTS-4 (aggrecanase-1).
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| Size | Price / USD | Stock | Quantity |
| 1 mL x 10 mM in DMSO | 98 | In Stock |
|
| 5MG | 85 | In Stock |
|
| 10MG | 124 | In Stock |
|
| 25MG | 204 | In Stock |
|
| 50MG | 298 | In Stock |
|
| 100MG | 429 | In Stock |
|
| 200MG | 600 | In Stock |
|
| 500MG | Get Quote | In Stock |
|
| 1G | Get Quote | In Stock |
|
Biological Information
-
Product NameADAMTS-5 Inhibitor
-
NoteResearch use only, not for human use.
-
Brief DescriptionADAMTS-5 Inhibitor is a potent ADAMTS-5 (aggrecanase-2) inhibitor, with an IC50 of 1.1 μM. ADAMTS-5 Inhibitor shows >40-fold functional selectivity over ADAMTS-4 (aggrecanase-1).
-
DescriptionADAMTS-5 Inhibitor is a potent ADAMTS-5 (aggrecanase-2) inhibitor, with an IC50 of 1.1 μM. ADAMTS-5 Inhibitor shows >40-fold functional selectivity over ADAMTS-4 (aggrecanase-1).
-
In Vitro——
-
In Vivo——
-
Synonyms——
-
PathwayOthers
-
TargetOther Targets
-
Recptor5-HT2A| D1 receptor| D5 receptor
-
Research Area——
-
Indication——
Chemical Information
-
CAS Number929634-33-3
-
Formula Weight449.91
-
Molecular FormulaC16H11ClF3N3OS3
-
Purity>98% (HPLC)
-
SolubilityIn Vitro:?DMSO : 83.33 mg/mL (185.21 mM)
-
SMILESCn1nc(c(\C=C2/SC(=S)NC2=O)c1SCc1ccc(Cl)cc1)C(F)(F)F
-
Chemical Name——
Shipping & Storage Information
-
Storage(-20℃)
-
ShippingWith Ice Pack
-
Stability≥ 2 years
Reference
1.1. Rostom SA. Novel fused pyrrole heterocyclic ring systems as structure analogs of LE 300: Synthesis and pharmacological evaluation as serotonin 5-HT(2A), dopamine and histamine H(1) receptor ligands. Arch Pharm (Weinheim). 2010 Feb;343(2):73-80.
molnova catalog
related products
-
E235
E235 is a regulatory activator of transcription factor 4 (ATF4) with antiproliferative activity.E235 acts by initiating the integrated stress response (ISR) and signaling the DNA damage response.
-
Human IgE Pentapepti...
Pentigetide is a sythsis pepetide (Asp-Ser-Asp-Pro-Arg or D-S-D-P-R), also know as “HEPP” for “Human IgE Pentapeptide”. Pentigetide can not produce IgE inhibition in several different systems, due to the aspartic acids in HEPP changed into an asparagine.
-
3,5-Dibromo-4-methox...
3,5-Dibromo-4-methoxybenzoic acid was isolated from the Malagasy sponge Amphimedon sp.
