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(R)-ADX-47273
CAS No. 851881-59-9
(R)-ADX-47273( —— )
Catalog No. M26528 CAS No. 851881-59-9
(R)-ADX-47273 is a potent mGluR5 positive allosteric modulator(EC50 of 168 nM for potentiation ).
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| Size | Price / USD | Stock | Quantity |
| 2MG | 61 | Get Quote |
|
| 5MG | 102 | Get Quote |
|
| 10MG | 177 | Get Quote |
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| 25MG | 322 | Get Quote |
|
| 50MG | 528 | Get Quote |
|
| 100MG | 755 | Get Quote |
|
| 500MG | 1521 | Get Quote |
|
| 1G | Get Quote | Get Quote |
|
Biological Information
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Product Name(R)-ADX-47273
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NoteResearch use only, not for human use.
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Brief Description(R)-ADX-47273 is a potent mGluR5 positive allosteric modulator(EC50 of 168 nM for potentiation ).
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Description(R)-ADX-47273 is a potent mGluR5 positive allosteric modulator(EC50 of 168 nM for potentiation ).
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In Vitro(R)-ADX-47273 (ADX-47273 (5)) is a potent mGluR5 positive allosteric modulator with an EC50 for potentiation of 168 nM and a 9-fold shift of the glutamate response curve at 1 μM.
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In Vivo——
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Synonyms——
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PathwayNeuroscience
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TargetGluR
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RecptorLIM Kinase (LIMK)
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Research Area——
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Indication——
Chemical Information
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CAS Number851881-59-9
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Formula Weight369.372
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Molecular FormulaC20H17F2N3O2
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Purity>98% (HPLC)
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SolubilityIn Vitro:?DMSO : 100 mg/mL (270.74 mM)
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SMILESFc1ccc(cc1)C(=O)N1CCC[C@H](C1)c1nc(no1)-c1ccc(F)cc1
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Chemical Name——
Shipping & Storage Information
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Storage(-20℃)
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ShippingWith Ice Pack
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Stability≥ 2 years
Reference
1.Wu J, Liu S, Fan Z, Zhang L, Tian Y, Yang R. A novel and selective inhibitor of PKC ζ potently inhibits human breast cancer metastasis in vitro and in mice. Tumour Biol. 2016 Jun;37(6):8391-401.
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