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EHP-101
CAS No. 1818428-24-8
EHP-101( VCE-004.8 )
Catalog No. M26498 CAS No. 1818428-24-8
VCE-004.8 is a specific dual agonist of PPARγ and CB2 receptor with potent anti-inflammatory activity. VCE-004.8 attenuates adipogenesis and prevents diet-induced obesity.
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| Size | Price / USD | Stock | Quantity |
| 1 mL x 10 mM in DMSO | 250 | In Stock |
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| 5MG | 227 | In Stock |
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| 10MG | 377 | In Stock |
|
| 25MG | 619 | In Stock |
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| 50MG | 849 | In Stock |
|
| 100MG | 1144 | In Stock |
|
| 200MG | Get Quote | In Stock |
|
| 500MG | Get Quote | In Stock |
|
| 1G | Get Quote | In Stock |
|
Biological Information
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Product NameEHP-101
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NoteResearch use only, not for human use.
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Brief DescriptionVCE-004.8 is a specific dual agonist of PPARγ and CB2 receptor with potent anti-inflammatory activity. VCE-004.8 attenuates adipogenesis and prevents diet-induced obesity.
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DescriptionVCE-004.8 is a specific dual agonist of PPARγ and CB2 receptor with potent anti-inflammatory activity. VCE-004.8 attenuates adipogenesis and prevents diet-induced obesity.(In Vivo):In HFD mice, VCE-004.8 (injection; 20 mg/kg/day; for 3 weeks) induces a significant reduction in body weight gain, total fat mass, adipocyte volume, and plasma triglycerides levels. VCE-004.8 can also significantly improve glucose tolerance, reduce leptin levels (a sign of obesity) and increase the levels of adiponectin and glucagon (GLP-1 and GIP) .
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In Vitro——
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In VivoEtrinabdione (i.p.; 20 mg/kg/day; for 3 weeks) induces a significant reduction in body weight gain, total fat mass, adipocyte volume and plasma triglycerides levels in HFD mice. Etrinabdione can also significantly ameliorate glucose tolerance, reduce leptin levels (a marker of adiposity) and increase adiponectin and incretins (GLP-1 and GIP) levels.
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SynonymsVCE-004.8
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PathwayGPCR/G Protein
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TargetCannabinoid Receptor
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Recptor——
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Research Area——
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Indication——
Chemical Information
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CAS Number1818428-24-8
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Formula Weight433.592
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Molecular FormulaC28H35NO3
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Purity>98% (HPLC)
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SolubilityIn Vitro:?DMSO : 50 mg/mL (115.32 mM)
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SMILESCCCCCC1=C(NCc2ccccc2)C(=O)C([C@@H]2C=C(C)CC[C@H]2C(C)=C)=C(O)C1=O
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Chemical Name——
Shipping & Storage Information
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Storage(-20℃)
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ShippingWith Ice Pack
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Stability≥ 2 years
Reference
1.Zhang J, Sayer EJ, Zhou J, Li Y, Li Y, Li Z, Wang F. Long-term fertilization modifies the mineralization of soil organic matter in response to added substrate. Sci Total Environ. 2021 Dec 1;798:149341.
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