SMS1-IN-1( —— )

Catalog No. M26452 CAS No. 1807943-38-9

SMS1-IN-1 is a potent inhibitor of sphingomyelin synthase 1 (SMS1, IC50 = 2.1 μM), and can be used in the atherosclerosis studies.

Purity : >98% (HPLC)

COA

Datasheet

HNMR

HPLC

MSDS

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Biological Information

Product Name

SMS1-IN-1
Note

Research use only, not for human use.
Brief Description

SMS1-IN-1 is a potent inhibitor of sphingomyelin synthase 1 (SMS1, IC50 = 2.1 μM), and can be used in the atherosclerosis studies.
Description

SMS1-IN-1 is a potent inhibitor of sphingomyelin synthase 1 (SMS1, IC50 = 2.1 μM), and can be used in the atherosclerosis studies. (In Vitro):SMS1-IN-1 (2.5, 10 and 50 μM) shows inhibitory effect against SMS1 in a dose-dependent manner.
In Vitro

——
In Vivo

——
Synonyms

——
Pathway

Others
Target

Other Targets
Recptor

D2 receptor| D3 receptor
Research Area

——
Indication

——

Chemical Information

CAS Number

1807943-38-9
Formula Weight

503.41
Molecular Formula

C23H23BrN2O4S
Purity

>98% (HPLC)
Solubility

In Vitro:?DMSO : 250 mg/mL (496.61 mM)
SMILES

Brc1ccc(CNC(=O)COc2ccc(cc2)S(=O)(=O)NCCc2ccccc2)cc1
Chemical Name

——

Shipping & Storage Information

Storage

(-20℃)
Shipping

With Ice Pack
Stability

≥ 2 years

Reference

1.Holmes et al (2010) The identification of a selective DA D2 partial agonist, D3 antagonist displaying high levels of brain exposure. Bioorg.Med.Chem.Lett. 20 2013

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