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SHIP2-IN-1
CAS No. 2252247-80-4
SHIP2-IN-1( —— )
Catalog No. M26440 CAS No. 2252247-80-4
SHIP2-IN-1 is a potent SHIP2 inhibitor(IC50 : 2 μM),and used in the research of Alzheimer’s disease.
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| Size | Price / USD | Stock | Quantity |
| 1 mL x 10 mM in DMSO | 181 | In Stock |
|
| 5MG | 164 | In Stock |
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| 10MG | 259 | In Stock |
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| 25MG | 429 | In Stock |
|
| 50MG | 591 | In Stock |
|
| 100MG | 798 | In Stock |
|
| 200MG | 1070 | In Stock |
|
| 500MG | Get Quote | In Stock |
|
| 1G | Get Quote | In Stock |
|
Biological Information
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Product NameSHIP2-IN-1
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NoteResearch use only, not for human use.
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Brief DescriptionSHIP2-IN-1 is a potent SHIP2 inhibitor(IC50 : 2 μM),and used in the research of Alzheimer’s disease.
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DescriptionSHIP2-IN-1 is a potent SHIP2 inhibitor(IC50 : 2 μM),and used in the research of Alzheimer’s disease.(In Vitro):PI(3,4)P2 production in HT22 cellssignificantly inhibited by SHIP2-IN-1 (10 μM) .
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In VitroSHIP2-IN-1 (Compound 43; 10 μM) significantly inhibits PI(3,4)P2 production in HT22 cells.
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In Vivo——
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Synonyms——
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PathwayMetabolic Enzyme/Protease
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TargetPhosphatase
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Recptorα4β1δ GABAA receptor| α4β3δ GABAA receptor| αβγ GABAA receptor
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Research Area——
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Indication——
Chemical Information
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CAS Number2252247-80-4
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Formula Weight379.22
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Molecular FormulaC17H13Cl2FN4O
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Purity>98% (HPLC)
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SolubilityIn Vitro:?DMSO : 100 mg/mL (263.70 mM)
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SMILESC[C@@H](Oc1cncc(c1)-c1cnc(N)nc1)c1c(Cl)ccc(F)c1Cl
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Chemical Name——
Shipping & Storage Information
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Storage(-20℃)
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ShippingWith Ice Pack
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Stability≥ 2 years
Reference
1.Hoestgaard-Jensen K, et al. Probing α4βδ GABAA receptor heterogeneity: differential regional effects of a functionally selective α4β1δ/α4β3δ receptor agonist on tonic and phasic inhibition in rat brain. J Neurosci. 2014 Dec 3;34(49):16256-72.
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