Sapienic acid sodium( —— )

Catalog No. M26431 CAS No. 217477-25-3

COA

Datasheet

HNMR

HPLC

MSDS

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Product Name

Sapienic acid sodium
Note

Research use only, not for human use.
Brief Description

Sapienic acid sodium is a fatty acid commonly. It has variable antimicrobial activities against Gram-positive and Gram-negative bacteria found on the skin and in the oral cavity.
Description

Sapienic acid sodium is a fatty acid commonly. It has variable antimicrobial activities against Gram-positive and Gram-negative bacteria found on the skin and in the oral cavity.(In Vitro):Sapienic acid is active against Streptococcus sanguinis, Streptococcus mitis, and Fusobacterium nucleatum. Kinetic assays show that killing of S. sanguinis and S. mitis with sapienic acid is gradual and occurred within 24 h.
In Vitro

Sapienic acid (minimum bactericidal concentrations (MBCs) range, 31.3 to 375.0 μg/mL) is active against Streptococcus sanguinis, Streptococcus mitis, and Fusobacterium nucleatum but not active against Escherichia coli, Staphylococcus aureus, S. marcescens, P. aeruginosa, Corynebacterium bovis, Corynebacterium striatum, and Corynebacterium jeikeium (MBC > 500 μg/mL). Kinetic assays show that killing of S. sanguinis and S. mitis with sapienic acid is gradual and occurred within 24 h.
In Vivo

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Synonyms

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Pathway

Others
Target

Other Targets
Recptor

BRAG2
Research Area

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Indication

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1.Nawrotek A, et al. PH-domain-binding inhibitors of nucleotide exchange factor BRAG2 disrupt Arf GTPase signaling. Nat Chem Biol. 2019 Feb 11.

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