Rezafungin

Research use only, not for human use.

Rezafungin is a broad-spectrum and long-lasting echinocandin with potent antifungal activity against Candida, Aspergillus and Pneumocystis.

Rezafungin is a broad-spectrum and long-lasting echinocandin with potent antifungal activity against Candida, Aspergillus and Pneumocystis.(In Vivo):Intraperitoneal injection of 1 mg/kg of Rezafungin once daily for 6 days in mice showed effective in vivo prevention of Pneumocystis spp., significantly reducing nuclear and asci burden in a C3H/HeN mouse infection model.

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Rezafungin (Biafungin) shows potent in vivo efficacy as prophylaxis against Pneumocystis in a mouse infection model. Animal Model:C3H/HeN mice Dosage:1 mg/kgA dministration:Intraperitoneal injection; once daily for 6 days Result:Significantly reduced nuclei and asci burdens.

Biafungin | CD101 | SP-3025

Others

Other Targets

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1396640-59-7

1226.411

C63H85N8O17

>98% (HPLC)

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[H][C@@]12C[C@@H](O)CN1C(=O)[C@@]([H])(NC(=O)[C@H](C[C@@H](O)[C@]([H])(NC(=O)[C@]1([H])[C@@H](O)[C@@H](C)CN1C(=O)[C@@]([H])(NC(=O)[C@@]([H])(NC2=O)[C@H](O)[C@@H](O)c1ccc(O)cc1)[C@@H](C)O)OCC[N+](C)(C)C)NC(=O)c1ccc(cc1)-c1ccc(cc1)-c1ccc(OCCCCC)cc1)[C@@H](C)O

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(-20℃)

With Ice Pack

≥ 2 years