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(Rac)-AMG8379

CAS No. 1641574-26-6

(Rac)-AMG8379( (Rac)-AMG8380 )

Catalog No. M26409 CAS No. 1641574-26-6

(Rac)-AMG8379 is a racemate of AMG8379. AMG8379 is a potent, orally active and selective sulfonamide NaV1.7 antagonist(hNaV1.7 and mNaV1.7 with IC50s of 8.5 and 18.6 nM , respectively ).

Purity : >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
Size Price / USD Stock Quantity
1 mL x 10 mM in DMSO 540 In Stock
2MG 278 In Stock
5MG 426 In Stock
10MG 625 In Stock
25MG 938 In Stock
50MG 1283 In Stock
100MG 1758 In Stock
200MG Get Quote In Stock
500MG 3515 In Stock
1G Get Quote In Stock
Get Quotation Bulk Inquiry Add to Cart

Biological Information

  • Product Name
    (Rac)-AMG8379
  • Note
    Research use only, not for human use.
  • Brief Description
    (Rac)-AMG8379 is a racemate of AMG8379. AMG8379 is a potent, orally active and selective sulfonamide NaV1.7 antagonist(hNaV1.7 and mNaV1.7 with IC50s of 8.5 and 18.6 nM , respectively ).
  • Description
    (Rac)-AMG8379 is a racemate of AMG8379. AMG8379 is a potent, orally active and selective sulfonamide NaV1.7 antagonist(hNaV1.7 and mNaV1.7 with IC50s of 8.5 and 18.6 nM , respectively ).
  • In Vitro
    ——
  • In Vivo
    ——
  • Synonyms
    (Rac)-AMG8380
  • Pathway
    Others
  • Target
    Other Targets
  • Recptor
    ATF4| ATF6| ERK| GRP78| MMP
  • Research Area
    ——
  • Indication
    ——

Chemical Information

  • CAS Number
    1641574-26-6
  • Formula Weight
    543.93
  • Molecular Formula
    C25H16ClF2N3O5S
  • Purity
    >98% (HPLC)
  • Solubility
    ——
  • SMILES
    O=S(NC1=NOC=C1)(C2=CC(C=CC(N3C4=CC(F)=C(C=C4OC)C5=CC(Cl)=CC(F)=C5)=O)=C3C=C2)=O.[Racemate]
  • Chemical Name
    ——

Shipping & Storage Information

  • Storage
    (-20℃)
  • Shipping
    With Ice Pack
  • Stability
    ≥ 2 years

Reference

1.Zhang B, Han H, et al. Dehydroeffusol inhibits gastric cancer cell growth and tumorigenicity by selectively inducing tumor-suppressive endoplasmic reticulum stress and a moderate apoptosis. Biochem Pharmacol. 2016 Mar 15;104:8-18.
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