Cart
sales@molnova.com
PD 168568 dihydrochloride
CAS No. 1782532-06-2
PD 168568 dihydrochloride( PD 168568 (dihydrochloride) )
Catalog No. M26360 CAS No. 1782532-06-2
PD 168568 dihydrochloride is an orally active and selective antagonist of D4 dopamine receptor(Ki of 8.8 nM).
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| Size | Price / USD | Stock | Quantity |
| 1 mL x 10 mM in DMSO | 52 | In Stock |
|
| 5MG | 38 | In Stock |
|
| 10MG | 50 | In Stock |
|
| 25MG | 113 | In Stock |
|
| 50MG | 166 | In Stock |
|
| 100MG | 242 | In Stock |
|
| 200MG | 340 | In Stock |
|
| 500MG | Get Quote | In Stock |
|
| 1G | Get Quote | In Stock |
|
Biological Information
-
Product NamePD 168568 dihydrochloride
-
NoteResearch use only, not for human use.
-
Brief DescriptionPD 168568 dihydrochloride is an orally active and selective antagonist of D4 dopamine receptor(Ki of 8.8 nM).
-
DescriptionPD 168568 dihydrochloride is an orally active and selective antagonist of D4 dopamine receptor(Ki of 8.8 nM).(In Vitro):PD 168568 dihydrochloride has good selective for D4 receptor(Ki of 1842 nM for D2 receptor).(In Vivo):PD 168568 dihydrochloride inhibit amphetamine stimulated locomotor activity in the rat.
-
In Vitro——
-
In VivoAnimal Model:Rat Dosage:3 mg/kg Administration:Oral administration Result:Inhibit amphetamine (0.5 mg/kg, i.p.) stimulated locomotor activity.
-
SynonymsPD 168568 (dihydrochloride)
-
PathwayGPCR/G Protein
-
TargetDopamine Receptor
-
Recptorα4β2 nAChR| α7 nAChR
-
Research Area——
-
Indication——
Chemical Information
-
CAS Number1782532-06-2
-
Formula Weight422.39
-
Molecular FormulaC22H29Cl2N3O
-
Purity>98% (HPLC)
-
Solubility——
-
SMILESCl.Cl.Cc1ccc(cc1C)N1CCN(CCC2NC(=O)c3ccccc23)CC1
-
Chemical Name——
Shipping & Storage Information
-
Storage(-20℃)
-
ShippingWith Ice Pack
-
Stability≥ 2 years
Reference
1.Stevens KE, Kem WR, Mahnir VM, Freedman R. Selective alpha7-nicotinic agonists normalize inhibition of auditory response in DBA mice. Psychopharmacology (Berl). 1998 Apr;136(4):320-7.
molnova catalog
related products
-
Dopamine
Dopamine is an inotropic vasopressor agent and dopamine receptor agonist used in neurological diseases.?
-
GSK 789472 hydrochlo...
GSK 789472 hydrochloride is both a dopamine D3 receptor antagonist and a D2 partial agonist.
-
Miriplatin
Miriplatin (SM-11355) is a platinum complex used in TACE that has promise for the therapy of hepatocellular carcinoma (HCC).
