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PD 168568 dihydrochloride
CAS No. 1782532-06-2
PD 168568 dihydrochloride( PD 168568 (dihydrochloride) )
Catalog No. M26360 CAS No. 1782532-06-2
PD 168568 dihydrochloride is an orally active and selective antagonist of D4 dopamine receptor(Ki of 8.8 nM).
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| Size | Price / USD | Stock | Quantity |
| 1 mL x 10 mM in DMSO | 52 | In Stock |
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| 5MG | 38 | In Stock |
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| 10MG | 50 | In Stock |
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| 25MG | 113 | In Stock |
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| 50MG | 166 | In Stock |
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| 100MG | 242 | In Stock |
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| 200MG | 340 | In Stock |
|
| 500MG | Get Quote | In Stock |
|
| 1G | Get Quote | In Stock |
|
Biological Information
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Product NamePD 168568 dihydrochloride
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NoteResearch use only, not for human use.
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Brief DescriptionPD 168568 dihydrochloride is an orally active and selective antagonist of D4 dopamine receptor(Ki of 8.8 nM).
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DescriptionPD 168568 dihydrochloride is an orally active and selective antagonist of D4 dopamine receptor(Ki of 8.8 nM).(In Vitro):PD 168568 dihydrochloride has good selective for D4 receptor(Ki of 1842 nM for D2 receptor).(In Vivo):PD 168568 dihydrochloride inhibit amphetamine stimulated locomotor activity in the rat.
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In Vitro——
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In VivoAnimal Model:Rat Dosage:3 mg/kg Administration:Oral administration Result:Inhibit amphetamine (0.5 mg/kg, i.p.) stimulated locomotor activity.
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SynonymsPD 168568 (dihydrochloride)
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PathwayGPCR/G Protein
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TargetDopamine Receptor
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Recptorα4β2 nAChR| α7 nAChR
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Research Area——
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Indication——
Chemical Information
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CAS Number1782532-06-2
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Formula Weight422.39
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Molecular FormulaC22H29Cl2N3O
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Purity>98% (HPLC)
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Solubility——
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SMILESCl.Cl.Cc1ccc(cc1C)N1CCN(CCC2NC(=O)c3ccccc23)CC1
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Chemical Name——
Shipping & Storage Information
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Storage(-20℃)
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ShippingWith Ice Pack
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Stability≥ 2 years
Reference
1.Stevens KE, Kem WR, Mahnir VM, Freedman R. Selective alpha7-nicotinic agonists normalize inhibition of auditory response in DBA mice. Psychopharmacology (Berl). 1998 Apr;136(4):320-7.
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