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NCGC00229600

CAS No. 1338824-20-6

NCGC00229600( —— )

Catalog No. M26326 CAS No. 1338824-20-6

NCGC00229600 is an allosteric inverse thyrotropin receptor (TSHR) agonist.

Purity : >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
Size Price / USD Stock Quantity
1 mL x 10 mM in DMSO 147 In Stock
5MG 141 In Stock
10MG 212 In Stock
25MG 372 In Stock
50MG 550 In Stock
100MG 830 In Stock
200MG 1097 In Stock
500MG Get Quote In Stock
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Biological Information

  • Product Name
    NCGC00229600
  • Note
    Research use only, not for human use.
  • Brief Description
    NCGC00229600 is an allosteric inverse thyrotropin receptor (TSHR) agonist.
  • Description
    NCGC00229600 is an allosteric inverse thyrotropin receptor (TSHR) agonist. NCGC00229600 inhibits both TSH and stimulating antibody activation of TSHRs endogenously and can be used in Graves' disease studies.
  • In Vitro
    ——
  • In Vivo
    ——
  • Synonyms
    ——
  • Pathway
    Others
  • Target
    Other Targets
  • Recptor
    NF-κB
  • Research Area
    ——
  • Indication
    ——

Chemical Information

  • CAS Number
    1338824-20-6
  • Formula Weight
    479.58
  • Molecular Formula
    C30H29N3O3
  • Purity
    >98% (HPLC)
  • Solubility
    In Vitro:?DMSO : 50 mg/mL (104.26 mM)
  • SMILES
    COc1ccc(cc1COc1c(C)cccc1C)C1Nc2ccccc2C(=O)N1Cc1cccnc1
  • Chemical Name
    ——

Shipping & Storage Information

  • Storage
    (-20℃)
  • Shipping
    With Ice Pack
  • Stability
    ≥ 2 years

Reference

1.Neelakantan S, et al. Aminoparthenolides as novel anti-leukemic agents: Discovery of the NF-kappaB inhibitor, DMAPT (LC-1). Bioorg Med Chem Lett. 2009 Aug 1;19(15):4346-9.
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