Duocarmycin TM

CAS No. 157922-77-5

Duocarmycin TM( —— )

Catalog No. M26182 CAS No. 157922-77-5

Duocarmycin TM is a DNA alkylator. Duocarmycin TM is an exceptionally potent antitumor antibiotic.

Purity : >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
Size Price / USD Stock Quantity
5MG 356 Get Quote
10MG 530 Get Quote
25MG 851 Get Quote
50MG 1152 Get Quote
100MG Get Quote Get Quote
200MG Get Quote Get Quote
500MG Get Quote Get Quote
1G Get Quote Get Quote

Biological Information

  • Product Name
    Duocarmycin TM
  • Note
    Research use only, not for human use.
  • Brief Description
    Duocarmycin TM is a DNA alkylator. Duocarmycin TM is an exceptionally potent antitumor antibiotic.
  • Description
    Duocarmycin TM is a DNA alkylator. Duocarmycin TM is an exceptionally potent antitumor antibiotic.
  • In Vitro
    Duocarmycin TM (60 μM; 4 d; BJAB and WSU-DLCL2 cells) is a cytotoxic agent that inhibits the proliferation of tumor cells.Cell Viability Assay Cell Line:BJAB and WSU-DLCL2 cells Concentration:60 μM Incubation Time:4 days Result:Inhibited the proliferation of tumor cells with IC50 values of 0.153 μM and 0.079μM for BJAB and WSU-DLCL2 cells, respectively.
  • In Vivo
    ——
  • Synonyms
    ——
  • Pathway
    Cell Cycle/DNA Damage
  • Target
    DNA Alkylator
  • Recptor
    ——
  • Research Area
    ——
  • Indication
    ——

Chemical Information

  • CAS Number
    157922-77-5
  • Formula Weight
    466.92
  • Molecular Formula
    C25H23ClN2O5
  • Purity
    >98% (HPLC)
  • Solubility
    In Vitro:?DMSO : ≥ 50 mg/mL (107.09 mM)
  • SMILES
    COc1cc2cc([nH]c2c(OC)c1OC)C(=O)N1C[C@@H](CCl)c2c1cc(O)c1ccccc21
  • Chemical Name
    ——

Shipping & Storage Information

  • Storage
    (-20℃)
  • Shipping
    With Ice Pack
  • Stability
    ≥ 2 years

Reference

1.Uddin MJ, et al. Synthesis of 5- and 6-carboxy-X-rhodamines. Org Lett. 2008 Nov 6;10(21):4799-801.
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