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Clocapramine dihydrochloride hydrate
CAS No. 60789-62-0
Clocapramine dihydrochloride hydrate( —— )
Catalog No. M26121 CAS No. 60789-62-0
Clocapramine hydrochloride hydrate is an antagonist of the 5-HT2A and D2 receptors.
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| Size | Price / USD | Stock | Quantity |
| 5MG | 1008 | Get Quote |
|
| 10MG | 1341 | Get Quote |
|
| 25MG | 2007 | Get Quote |
|
| 50MG | 2664 | Get Quote |
|
| 100MG | 3573 | Get Quote |
|
| 200MG | Get Quote | Get Quote |
|
| 500MG | Get Quote | Get Quote |
|
| 1G | Get Quote | Get Quote |
|
Biological Information
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Product NameClocapramine dihydrochloride hydrate
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NoteResearch use only, not for human use.
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Brief DescriptionClocapramine hydrochloride hydrate is an antagonist of the 5-HT2A and D2 receptors.
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DescriptionClocapramine hydrochloride hydrate is an antagonist of the 5-HT2A and D2 receptors.(In Vivo):Clocapramine shows the lowest potency for D2-occupancy in vivo . An in vivo receptor binding technique is used to evaluate the binding profiles of typical and atypical antipsychotic drugs to striatal dopamine-D2 and frontal serotonin-5-HT2 receptors in a rat brain using more specific ligands. Clocapramine produces ratios of potency in occupying 5-HT2 versus D2 receptors that fall between these two groups (ED50s: 14.5 mg/kg for D2, 4.9 mg/kg for 5-HT2) .
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In Vitro——
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In VivoClocapramine shows the lowest potency for D2-occupancy in vivo. An in vivo receptor binding technique is used to evaluate the binding profiles of typical and atypical antipsychotic drugs to striatal dopamine-D2 and frontal serotonin-5-HT2 receptors in a rat brain using more specific ligands. Clocapramine produces ratios of potency in occupying 5-HT2 versus D2 receptors that fall between these two groups (ED50 of 14.5 mg/kg for D2, 4.9 mg/kg for 5-HT2).
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Synonyms——
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PathwayOthers
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TargetOther Targets
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RecptorWnt
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Research Area——
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Indication——
Chemical Information
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CAS Number60789-62-0
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Formula Weight572.01
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Molecular FormulaC28H41Cl3N4O2
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Purity>98% (HPLC)
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Solubility——
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SMILESO.Cl.Cl.NC(=O)C1(CCN(CCCN2c3ccccc3CCc3ccc(Cl)cc23)CC1)N1CCCCC1
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Chemical Name——
Shipping & Storage Information
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Storage(-20℃)
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ShippingWith Ice Pack
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Stability≥ 2 years
Reference
1.Charlene F. Barroga, et al. Diketones and hydroxyketones as catenin signaling pathway activators. WO2012024404A1.
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