Cart
sales@molnova.com
Autogramin-1
CAS No. 2375541-73-2
Autogramin-1( —— )
Catalog No. M26065 CAS No. 2375541-73-2
Autogramin-1 potently inhibits starvation-induced autophagy with IC50 of 0.17 μM.
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| Size | Price / USD | Stock | Quantity |
| 5MG | 334 | In Stock |
|
| 10MG | 468 | In Stock |
|
| 25MG | 730 | In Stock |
|
| 50MG | 918 | In Stock |
|
| 100MG | 1293 | In Stock |
|
| 200MG | Get Quote | In Stock |
|
| 500MG | 2595 | In Stock |
|
| 1G | Get Quote | In Stock |
|
Biological Information
-
Product NameAutogramin-1
-
NoteResearch use only, not for human use.
-
Brief DescriptionAutogramin-1 potently inhibits starvation-induced autophagy with IC50 of 0.17 μM.
-
DescriptionAutogramin-1 potently inhibits starvation-induced autophagy with IC50 of 0.17 μM. Autogramin-1 also inhibits Rapamycin (mTORC1)-induced autophagy with IC50 of 0.44 μM.
-
In Vitro——
-
In Vivo——
-
Synonyms——
-
PathwayPI3K/Akt/mTOR signaling
-
TargetmTOR
-
RecptorP2X3
-
Research Area——
-
Indication——
Chemical Information
-
CAS Number2375541-73-2
-
Formula Weight485.56
-
Molecular FormulaC23H27N5O5S
-
Purity>98% (HPLC)
-
SolubilityIn Vitro:?DMSO : 6.94 mg/mL (14.29 mM)
-
SMILESCCCn1c(=O)[nH]c2cc(ccc2c1=O)C(=O)Nc1nc2CCN(Cc2s1)C(=O)OC(C)(C)C
-
Chemical Name——
Shipping & Storage Information
-
Storage(-20℃)
-
ShippingWith Ice Pack
-
Stability≥ 2 years
Reference
1.Spinaci A, et, al. P2X3 Receptor Ligands: Structural Features and Potential Therapeutic Applications. Front Pharmacol. 2021 Apr 13;12:653561.
molnova catalog
related products
-
mTOR inhibitor 9e
mTOR inhibitor 9e is a selective mTOR inhibitor with IC50 of 0.68nM and 1359nM for mTOR and PI3Kα, respectively.
-
mTOR inhibitor-8
mTOR inhibitor-8 is a potent mTOR inhibitor and autophagy inducer with antiviral and antitumor activity. mTOR inhibitor-8 inhibits the growth of A549 cells, which can be used to study non-small cell lung cancer.
-
Seco Rapamycin
Seco-rapamycin is the first in vivo open-ring metabolite of rapamycin that does not affect mTOR.
