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DPA-714
CAS No. 958233-07-3
DPA-714( —— )
Catalog No. M25016 CAS No. 958233-07-3
DPA-714 is a high affinity translocator protein (TSPO) ligand (Ki=7 nM).
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| Size | Price / USD | Stock | Quantity |
| 1 mL x 10 mM in DMSO | 188 | In Stock |
|
| 5MG | 180 | In Stock |
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| 10MG | 269 | In Stock |
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| 25MG | 499 | In Stock |
|
| 50MG | 709 | In Stock |
|
| 100MG | 1004 | In Stock |
|
| 200MG | 1386 | In Stock |
|
| 500MG | Get Quote | In Stock |
|
| 1G | Get Quote | In Stock |
|
Biological Information
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Product NameDPA-714
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NoteResearch use only, not for human use.
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Brief DescriptionDPA-714 is a high affinity translocator protein (TSPO) ligand (Ki=7 nM).
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DescriptionDPA-714 is a high affinity translocator protein (TSPO) ligand (Ki=7 nM). It is designed with a fluorine atom in its structure, allowing labelling with fluorine -18 and in vivo imaging using positron emission tomography. [18F]DPA-714 successfully assesses for the specific imaging of inflammation in various models of neuroinflammation and in a brain tumor model.
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In Vitro——
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In Vivo[18F]DPA-714 binding significantly increases in vivo as a result of AD‐like pathology and age in APPswe×PS1Δe9 mice.
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Synonyms——
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PathwayOthers
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TargetOther Targets
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RecptorTSPO
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Research Area——
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Indication——
Chemical Information
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CAS Number958233-07-3
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Formula Weight398.47
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Molecular FormulaC22H27FN4O2
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Purity>98% (HPLC)
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SolubilityDMSO:41.67 mg/mL (104.57 mM; Need ultrasonic)
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SMILESCCN(CC)C(Cc1c2nc(C)cc(C)n2nc1-c(cc1)ccc1OCCF)=O
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Chemical Name——
Shipping & Storage Information
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Storage(-20℃)
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ShippingWith Ice Pack
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Stability≥ 2 years
Reference
1.James ML, et al. DPA-714, a new translocator protein-specific ligand: synthesis, radiofluorination, and pharmacologic characterization. J Nucl Med. 2008 May;49(5):814-22.
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