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SEC inhibitor KL-1
CAS No. 900308-84-1
SEC inhibitor KL-1( KL-1 )
Catalog No. M24926 CAS No. 900308-84-1
SEC inhibitor KL-1 exhibits a dose-dependent inhibitory effect on AFF4-CCNT1 interaction (Ki: 3.48 μM).
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| Size | Price / USD | Stock | Quantity |
| 1 mL x 10 mM in DMSO | 87 | In Stock |
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| 2MG | 48 | In Stock |
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| 5MG | 79 | In Stock |
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| 10MG | 126 | In Stock |
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| 25MG | 216 | In Stock |
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| 50MG | 319 | In Stock |
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| 100MG | 454 | In Stock |
|
| 200MG | 631 | In Stock |
|
| 500MG | Get Quote | In Stock |
|
| 1G | Get Quote | In Stock |
|
Biological Information
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Product NameSEC inhibitor KL-1
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NoteResearch use only, not for human use.
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Brief DescriptionSEC inhibitor KL-1 exhibits a dose-dependent inhibitory effect on AFF4-CCNT1 interaction (Ki: 3.48 μM).
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DescriptionSEC inhibitor KL-1 exhibits a dose-dependent inhibitory effect on AFF4-CCNT1 interaction (Ki: 3.48 μM). SEC inhibitor KL-1 is a potent, selective super elongation complex (SEC) inhibitor and disrupts the interaction between the SEC scaffolding protein AFF4.
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In Vitro——
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In Vivo——
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SynonymsKL-1
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PathwayOthers
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TargetOther Targets
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RecptorSEC
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Research Area——
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Indication——
Chemical Information
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CAS Number900308-84-1
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Formula Weight345.78
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Molecular FormulaC18H16ClNO4
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Purity>98% (HPLC)
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SolubilityDMSO:41.67 mg/mL (120.51 mM; Need ultrasonic)
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SMILESCC1=C(C=C(C=C1)Cl)NC(=O)C(=O)CC(=O)C2=CC(=CC=C2)OC
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Chemical Name——
Shipping & Storage Information
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Storage(-20℃)
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ShippingWith Ice Pack
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Stability≥ 2 years
Reference
1.Liang K, et al. Targeting Processive Transcription Elongation via SEC Disruption for MYC-Induced CancerTherapy. Cell. 2018 Oct 18;175(3):766-779.
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