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CCG-143140
CAS No. 891016-02-7
CCG-143140( ML-SI3 )
Catalog No. M24914 CAS No. 891016-02-7
CCG-143140 is a GLP-1 receptor inverse agonists.
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| Size | Price / USD | Stock | Quantity |
| 1 mL x 10 mM in DMSO | 71 | In Stock |
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| 2MG | 40 | In Stock |
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| 5MG | 64 | In Stock |
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| 10MG | 112 | In Stock |
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| 25MG | 235 | In Stock |
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| 50MG | 365 | In Stock |
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| 100MG | 548 | In Stock |
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| 200MG | Get Quote | In Stock |
|
| 500MG | Get Quote | In Stock |
|
| 1G | Get Quote | In Stock |
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Biological Information
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Product NameCCG-143140
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NoteResearch use only, not for human use.
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Brief DescriptionCCG-143140 is a GLP-1 receptor inverse agonists.
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DescriptionCCG-143140 is a GLP-1 receptor inverse agonists.
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In VitroML-SI3 (10 μM) inhibits ML-SA1-evoked Ca2+ signals in HeLa cells.ML-SI3 (25-75 μM, 24h) disrupts tegumental integrity of adult schistosomes.ML-SI3 (10 μM) blocks Rapamycin (HY-10219)-evoked ITRPML1 in mimic of lysosomal lumen.ML-SI3 (3 μM, 6 h) abolishes the increase in both LC3II and p62 levels induced by hypoxia/reoxygenation (H/R) (4 h H/2 h R) in neonatal rat ventricular myocytes (NRVM).
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In VivoML-SI3 (1.5 mg/kg, i.p., four times) attenuates I/R injury in mouse cardiomyocytes. Animal Model:Myocardial Ischemia/reperfusion (I/R) injury miceDosage:1.5 mg/kg Administration:Intraperitoneal injection (i.p.), four times before and during the in vivo I/R (ischemia 30 min and reperfusion 1 day)Result:Restored the blocked autophagic fux in the cardiomyocytes subjected to I/R.
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SynonymsML-SI3
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PathwayGPCR/G Protein
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TargetGlucagon Receptor
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RecptorGLP-1
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Research Area——
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Indication——
Chemical Information
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CAS Number891016-02-7
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Formula Weight429.58
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Molecular FormulaC23H31N3O3S
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Purity>98% (HPLC)
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SolubilityIn Vitro:?DMSO : 50 mg/mL (116.39 mM)
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SMILESO=S(C1=CC=CC=C1)(NC2C(N3CCN(C4=CC=CC=C4OC)CC3)CCCC2)=O
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Chemical Name——
Shipping & Storage Information
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Storage(-20℃)
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ShippingWith Ice Pack
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Stability≥ 2 years
Reference
molnova catalog
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